Native human IgG2 protein (azide free) (ab169742)

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Key features and details

  • Expression system: Native
  • Purity: > 95% SDS-PAGE
  • Suitable for: SDS-PAGE

Description

  • Product name

    Native human IgG2 protein (azide free)
    See all IgG2 proteins and peptides

  • Biological activity

    Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 and 2 by FDA approved tests.

  • Purity

    > 95 % SDS-PAGE.

  • Expression system

    Native

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Native

    • Species

      Human

    • Predicted molecular weight

      36 kDa

  • Description

    Native Human IgG2 protein (Azide free)

Specifications

Our Abpromise guarantee covers the use of ab169742 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Preservative: 0.05% Sodium azide
    Constituents: 0.87% Sodium chloride, 0.19% Phosphate Buffer

General Info

  • Alternative names

    • Ig gamma-2 chain C region
    • IGHG2
    • immunoglobulin Gm2
    • immunoglobulin heavy constant gamma 2 (G2m marker)
    • immunoglobulin heavy constant, gamma 2
    see all

  • Relevance

    There are four IgG subclasses (IgG1, 2, 3 and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant). IgG2 is the only IgG subclass which passes through the placenta at a level generally lower than that found in the mother. A deficiency of IgG2 indicates a poor antibody response to bacterial polysaccharides and can lead to increased susceptibility to infections caused by encapsulated bacteria.

  • Cellular localization

    Secreted

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab169742? Please let us know so that we can cite the reference in this datasheet.

ab169742 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Question

Is this IgG2 protein (Azide free) provided in any smaller unit size? Also, does this IgG2 have a variable region?

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Answer

Unfortunately, we do not offer a smaller aliquot of ab169742, and as the IgG2 is purified as a whole molecule, it does have a variable region.

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