Description

  • Product name

    Native Human IgG3 protein
    See all IgG3 proteins and peptides
  • Purity

    > 95 % SDS-PAGE.
    ab118426 is prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
  • Expression system

    Native
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Native
    • Species

      Human
    • Predicted molecular weight

      170 kDa

Specifications

Our Abpromise guarantee covers the use of ab118426 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Preservative: 0.05% Sodium azide
    Constituents: 0.32% Sodium phosphate, 0.88% Sodium chloride

General Info

  • Alternative names

    • DKFZp686H11213
    • FLJ39988
    • FLJ40036
    • FLJ40253
    • FLJ40587
    • FLJ40789
    • FLJ40834
    • HDC
    • Heavy chain disease protein
    • Ig gamma 3 chain C region
    • IGHG3
    • Immunoglobulin heavy constant gamma 3 (G3m marker)
    • MGC45809
    see all
  • Relevance

    IgG3, like IgG1, activates complement and has an affinity for fc receptors; thus IgG1 and IgG3 are the more effective of the IgG subclasses. An IgG3 deficiency is associated with Wiscott-Aldrich disease, systemic lupus erythematosus, juvenile diabetes mellitus, and peridontal infections. IgG anti-viral antibodies are restricted to IgG subclasses 1 and 3, with IgG3 antibodies being the first to appear in response to infection.
  • Cellular localization

    Secreted

Images

  • SDS PAGE analysis of ab118426 under reducing conditions (lanes 2-4) and non-reducing conditions (lanes 5-7) on 4 - 12% Bis-Tris NuPAGE gel.

    Lane 1: ladder.

    Lane 2: 5 μg (reduced / heated)

    Lane 3: 10 μg (reduced / heated)

    Lane 4: 20 μg (reduced / heated)

    Lane 5: 5 μg (non-reduced / no heat)

    Lane 6: 10 μg (non-reduced / no heat)

    Lane 7: 20 μg (non-reduced / no heat)

     

     

References

ab118426 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Question
Answer

Thank you once again for your recent enquiries.

I have now received information to confirm that ab118426 is purified from normal plasma, and shows no reaction to antisera to human IgA, IgD, IgE or IgM.

I hope this information is helpful to you. If you have any further questions, please do not hesitate to contact us.

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Answer

Thank you for your email.

I am happy to check these concentrations for you. Please find here below the answers:

IgG1 protein (ab90283) you will receive 1 mg at 3.41mg/ml, ¨so it will be in 293ul



IgG2 protein (ab90284) you will receive 1 mg at 2.2mg/ml, so it will be in 455ul



IgG3 protein (ab118426) you will receive 1 mg at 1.16mg/ml, so it will bein 862ul



IgG4 protein (ab90286) you will receive1mg at a lot dependent concentration, between 1.09-1.12mg/ml, which will be between 917ul and 893ul

I hope this information is helpful. Please do not hesitate to contact us again, should you need any additional information or should you have any questions.

I wish youa great day!

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