Product nameNative Human IgG3 protein
See all IgG3 proteins and peptides
Purity> 95 % SDS-PAGE.
ab118426 is prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Protein lengthFull length protein
Predicted molecular weight170 kDa
Our Abpromise guarantee covers the use of ab118426 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Preservative: 0.05% Sodium azide
Constituents: 0.32% Sodium phosphate, 0.88% Sodium chloride
RelevanceIgG3, like IgG1, activates complement and has an affinity for fc receptors; thus IgG1 and IgG3 are the more effective of the IgG subclasses. An IgG3 deficiency is associated with Wiscott-Aldrich disease, systemic lupus erythematosus, juvenile diabetes mellitus, and peridontal infections. IgG anti-viral antibodies are restricted to IgG subclasses 1 and 3, with IgG3 antibodies being the first to appear in response to infection.
SDS PAGE analysis of ab118426 under reducing conditions (lanes 2-4) and non-reducing conditions (lanes 5-7) on 4 - 12% Bis-Tris NuPAGE gel.
Lane 1: ladder.
Lane 2: 5 μg (reduced / heated)
Lane 3: 10 μg (reduced / heated)
Lane 4: 20 μg (reduced / heated)
Lane 5: 5 μg (non-reduced / no heat)
Lane 6: 10 μg (non-reduced / no heat)
Lane 7: 20 μg (non-reduced / no heat)
ab118426 has not yet been referenced specifically in any publications.