Description

Specifications

Our Abpromise guarantee covers the use of ab234553 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

  • Form

    Lyophilised
  • Additional notes

    Previously labelled as Sex Hormone Binding Globulin. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.

    Constituent: 0.16% Ammonium bicarbonate

General Info

  • Alternative names

    • ABP
    • Androgen binding protein
    • SBP
    • Sex hormone-binding globulin
    • Sex steroid binding protein
    • Sex steroid-binding protein
    • SHBG
    • SHBG_HUMAN
    • TeBG
    • Testis specific androgen binding protein
    • Testis-specific androgen-binding protein
    • Testosterone binding beta globulin
    • Testosterone estradiol binding globulin
    • Testosterone estrogen binding globulin
    • Testosterone-estradiol-binding globulin
    • Testosterone-estrogen-binding globulin
    see all
  • Function

    Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
  • Tissue specificity

    Isoform 1 and isoform 2 are present in liver and testis.
  • Sequence similarities

    Contains 2 laminin G-like domains.
  • Cellular localization

    Secreted. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
  • Information by UniProt

References

ab234553 has not yet been referenced specifically in any publications.

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