Key features and details
- Expression system: Native
- Purity: > 40% Affinity purified
- Suitable for: IA, ELISA
Product nameNative Human SHBG protein
See all SHBG proteins and peptides
Purity> 40 % Affinity purified.
Purified from human plasma. Sex Hormone Binding Globulin/SHBG protein is eluted from an affinity column using a competing ligand. After elution, the product is only subjected to buffer exchange by dialysis, which will not remove the tightly bound ligand. Consequently, the protein has a bound ligand still attached.
Protein lengthFull length protein
Predicted molecular weight45 kDa
Our Abpromise guarantee covers the use of ab151275 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Previously labelled as Sex Hormone Binding Globulin.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 0.24% HEPES, 0.87% Sodium chloride
- Androgen binding protein
FunctionFunctions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
Tissue specificityIsoform 1 and isoform 2 are present in liver and testis.
Sequence similaritiesContains 2 laminin G-like domains.
Cellular localizationSecreted. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab151275 has been referenced in 1 publication.
- Yamazaki H et al. Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages. Mediators Inflamm 2018:3062319 (2018). PubMed: 30046278