Product nameAnti-Natriuretic peptides A antibody
See all Natriuretic peptides A primary antibodies
DescriptionRabbit polyclonal to Natriuretic peptides A
Tested applicationsSuitable for: ICC, ICC/IF, RIAmore details
Species reactivityReacts with: Mouse, Rat
Predicted to work with: Guinea pig, Chimpanzee, Gorilla
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferConstituent: Whole serum
Our Abpromise guarantee covers the use of ab14348 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC||Use at an assay dependent dilution.|
|ICC/IF||Use at an assay dependent dilution. PubMed: 20544856|
FunctionHormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Involvement in diseaseAtrial standstill 2
Atrial fibrillation, familial, 6
Sequence similaritiesBelongs to the natriuretic peptide family.
modificationsCleaved by CORIN upon secretion to produce the functional hormone.
Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity.
- Information by UniProt
- ANF antibody
- ANF_HUMAN antibody
- ANP antibody
This product has been referenced in:
- Ravi V et al. Systematic evaluation of the adaptability of the non-radioactive SUnSET assay to measure cardiac protein synthesis. Sci Rep 8:4587 (2018). Read more (PubMed: 29545554) »
- Zheng C et al. Gastrodin Inhibits Store-Operated Ca(2+) Entry and Alleviates Cardiac Hypertrophy. Front Pharmacol 8:222 (2017). WB ; Mouse . Read more (PubMed: 28487655) »