Key features and details
- Goat polyclonal to Natriuretic peptides A - C-terminal
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-Natriuretic peptides A antibody - C-terminal
See all Natriuretic peptides A primary antibodies
DescriptionGoat polyclonal to Natriuretic peptides A - C-terminal
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Predicted to work with: Sheep, Horse, Guinea pig, Cow, Cat, Dog, Pig, Orangutan
- Human heart tissue, Mouse heart tissue lysate.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 99% Tris buffered saline
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab190001 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 µg/ml.|
|WB||Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 19 kDa (predicted molecular weight: 17 kDa).|
FunctionHormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Involvement in diseaseAtrial standstill 2
Atrial fibrillation, familial, 6
Sequence similaritiesBelongs to the natriuretic peptide family.
modificationsCleaved by CORIN upon secretion to produce the functional hormone.
Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity.
- Information by UniProt
- ANF antibody
- ANF_HUMAN antibody
- ANP antibody
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human heart tissue, labeling Natriuretic peptides A with ab190001 at 5 µg/ml.
Anti-Natriuretic peptides A antibody - C-terminal (ab190001) at 0.03 µg/ml + Mouse heart lysate at 35 µg
Developed using the ECL technique.
Predicted band size: 17 kDa
Observed band size: 19 kDa why is the actual band size different from the predicted?
Primary incubation was 1 hour.
ab190001 has been referenced in 2 publications.