For the best experience on the Abcam website please upgrade to a modern browser such as
Full length protein
Amino Acid Sequence
STSATDTHHVEMARERSKTVTSFYNQSAIDVAAEKPSVRLTPTMMLYSGR SQDGSHLLKSARYLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYI RAFQKLTDFPPIKDQADEARYCQLVRQLLDDHKDVVTLLAEGLRESRKYI EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKI IEKWVDFARRLCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNA MRATMESHLDTPYNVPDVVITIANNDIDLVIRISDRGGGIAHKDLDRVMD YHFTTAEASTQDPRISPLFGHLDLHSGGQSGPMHGFGFGLPTSRAYAEYL GGSLRLQSLQGIGTDVYLRLRHIDGREESFRI
31 to 412
Additional sequence information
subunit apparent Mr's 52,000 (E2), 46,000 (E1alpha), 35,000 (E1beta). Apparent Mr~ 3,200,000 by sedimentation equilibrium centrifugation.
Source = bovine kidney
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
~ 8-10 mmol of NADH formed per min per mg of protein with α-ketoisovalerate as substrate.
>90% by SDS-PAGE.
Concentration information loading...
Stability and Storage
Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Constituents: 0.79% Tris HCl, 0.11% Beta mercaptoethanol, 0.012% Benzamidine, 0.002% PMSF, 0.03% EDTA, 10% Glycerol
This product is an active protein and may elicit a biological response in vivo, handle with caution.
[3 methyl 2 oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase
Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex.
Belongs to the PDK/BCKDK protein kinase family.
Contains 1 histidine kinase domain.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"