Native Human Apo-H protein (ab62258)
Key features and details
- Expression system: Native
- Purity: > 95% SDS-PAGE
- Suitable for: ELISA, SDS-PAGE
Description
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Product name
Native Human Apo-H protein
See all Apo-H proteins and peptides -
Purity
> 95 % SDS-PAGE.
Purified using a combination of ion exchange and affinity chromatography. -
Expression system
Native -
Protein length
Full length protein -
Animal free
No -
Nature
Native -
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Species
Human
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Specifications
Our Abpromise guarantee covers the use of ab62258 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
ELISA
SDS-PAGE
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Form
Lyophilized -
Additional notes
Previously labelled as Apolipoprotein H.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituent: Glycine buffered saline
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ReconstitutionReconstitution by adding 1 ml of water for a final concentration of 0.1 mg/ml.
General Info
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Alternative names
- Activated protein C binding protein
- Activated protein C-binding protein
- Anticardiolipin cofactor
see all -
Function
Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. -
Tissue specificity
Expressed by the liver and secreted in plasma. -
Sequence similarities
Contains 4 Sushi (CCP/SCR) domains. -
Post-translational
modificationsN- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele. -
Cellular localization
Secreted. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (2)
ab62258 has been referenced in 2 publications.
- Liu YM et al. High expression of beta2-glycoprotein I is associated significantly with the earliest stages of hepatitis B virus infection. J Med Virol 86:1296-306 (2014). PubMed: 24760738
- Brochado MJ et al. Correlation between beta-2-glycoprotein I gene polymorphism and anti-beta-2 glycoprotein I antibodies in patients with multibacillary leprosy. Arch Dermatol Res 302:583-91 (2010). ELISA . PubMed: 20140737