Add 100µl deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at -80°C for long term storage.
Product is not sterile! Please filter the product by an appropriate sterile filter before using it in cell culture.
Bile salt-stimulated lipase
Carboxyl ester lipase
Carboxyl ester lipase (bile salt stimulated lipase)
Fetoacinar pancreatic protein
Defects in Bile salt activated lipase (CEL) are a cause of maturity onset diabetes of the young type 8 with exocrine dysfunction (MODY8) [MIM:609812], also known as diabetes and pancreatic exocrine dysfunction (DPED). MODY [MIM:606391] is an autosomal dominant form of diabetes mellitus. The pancreas serves both endocrine and exocrine functions. The endocrine cells are found in the islets of Langerhans. They synthesize insulin and other hormones, and are involved in the pathogenesis of diabetes mellitus. The exocrine cells produce bicarbonate and digestive enzymes and are involved in the pathogenesis of pancreatic malabsorption. The localization of the islets within exocrine pancreatic tissue is suggestive of an interdependency and cross talk between these two cell populations in their normal and in their abnormal function.
Cytoplasmic and Nuclear
SDS-PAGE - Natural Human Bile salt-activated lipase protein (ab167963)
12% SDS-PAGE analysis of ab167963 stained with Coomassie Brillant Blue G250.
Lane 1: MWt marker
Lane 2: reduced and boiled sample, 2.5 μg
Lane 3: non-reduced and non-boiled sample, 2.5 μg
has not yet been referenced specifically in any publications.
Publishing research using ab167963? Please let us know so that we can cite the reference in this datasheet.
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