Natural Human Cardiac Troponin T protein (ab9937)



  • Nature
  • Source
  • Amino Acid Sequence
    • Accession
    • Species
    • Sequence


Our Abpromise guarantee covers the use of ab9937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications


  • Form
  • Additional notes
    Native Human Cardiac Troponin-T
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 36.03% Urea, 0.117% Beta mercaptoethanol, 0.79% Tris HCl, 0.029% EDTA, 1.45% Sodium chloride

General Info

  • Alternative names
    • Cardiac muscle troponin T
    • Cardiomyopathy dilated 1D (autosomal dominant)
    • Cardiomyopathy hypertrophic 2
    • CMD1D
    • CMH2
    • CMPD2
    • cTnT
    • LVNC6
    • MGC3889
    • OTTHUMP00000033864
    • OTTHUMP00000033865
    • OTTHUMP00000033866
    • OTTHUMP00000033867
    • OTTHUMP00000033870
    • OTTHUMP00000218095
    • RCM3
    • TNNT 2
    • TNNT2
    • TnTc
    • Troponin T cardiac muscle
    • Troponin T type 2 (cardiac)
    • Troponin T type 2 cardiac
    • Troponin T, cardiac muscle
    • Troponin T2 cardiac
    see all
  • Function
    Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
  • Tissue specificity
    Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.
  • Involvement in disease
    Defects in TNNT2 are the cause of cardiomyopathy familial hypertrophic type 2 (CMH2) [MIM:115195]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
    Defects in TNNT2 are the cause of cardiomyopathy dilated type 1D (CMD1D) [MIM:601494]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
    Defects in TNNT2 are the cause of cardiomyopathy familial restrictive type 3 (RCM3) [MIM:612422]. Restrictive cardiomyopathy is a heart disorder characterized by impaired filling of the ventricles with reduced diastolic volume, in the presence of normal or near normal wall thickness and systolic function.
  • Sequence similarities
    Belongs to the troponin T family.
  • Information by UniProt


ab9937 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Thank you for contacting us.

Yes, I can confirm the ab105441is the biotinylated form of ab8295, and this antibody shows a good affinity towards the native protein as can be seen in the ELISA and IHC data.

I hope this informat...

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Thank you very much for your patience while I was investigating.

I am happy to confirm that we do have antibody pairs validated for sandwich ELISA for Troponin T, C and I. We do not have tested troponin proteins as standard. For the Trop...

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Thank you for your email. I am sorry for having generated a confusion. I will call you tomorrow morning (I guess this will be afternoon for you).

Meanwhile please have a look at our sandwich ELISA protocol. With "work together" I me...

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Thank you for your email.

The two antibodies will work together. The protein we do not know whether it will work in ELISA.

This is why we could give you a testing discount on the protein. This means, you would buy the protein to the...

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Thank you very much for your interest in our products.

I am happy to confirm that the ab8295 and the ab8296 are perfectly well choosen together. They will work as a sandwich pair in ELISA.

The ab9937, which you would use as a standa...

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Could you please specify for me which product your question is refering to: ab9937 or ab96516?

One of the most common compositions of PBS is as follows:

Salt Concentration Concentration

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For ab9937, the concentration was determined by A280, assuming an extinction coefficient of 16,960 cm-1 M-1 at 280 nm and a molecular weight of 34,575.

I hope this information is helpful to you. Please do not hesitate to contact us if you ne...

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Thank you for contacting us. I would recommend to use : 1) For the detection of Cardiac Troponin T : - ab45932 as capture antibody (directed against amino acids 64-82) , - ab9937 as protein target, www.abcam.c...

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Thank you for you enquiry. Unfortunately we do not have details of the charge of cardiac Troponin T protein (ab9937) on our data sheet. However, I have done some literature searching and according to Pearlstone et al., (1986) (see the link below) the p...

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