Natural human hCG protein (ab77874)



  • Nature
  • Amino Acid Sequence
    • Species


Our Abpromise guarantee covers the use of ab77874 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Activity: 14,527 U/mg (Abbott Axsym).
  • Applications


  • Purity
    > 95 % SDS-PAGE.
    >96% pure (SDS-PAGE) Contaminants: LH <0.008% (Abbott Axsym) FSH <0.002% (Abbott Axsym) TSH none detected (Abbott Axsym)
  • Form
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C.

    Not applicable

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstitute using deionized water.

General Info

  • Alternative names
    • anterior pituitary glycoprotein hormones common subunit alpha
    • CG alpha
    • CG-ALPHA
    • CGB
    • CGB3
    • CGB5
    • CGB7
    • choriogonadotropin alpha chain
    • Chorionic gonadotrophin chain beta
    • chorionic gonadotrophin subunit alpha
    • chorionic gonadotropin beta 3 subunit
    • Chorionic gonadotropin beta chain
    • Chorionic gonadotropin beta subunit
    • chorionic gonadotropin, alpha polypeptide
    • chorionic gonadotropin, beta polypeptide
    • chorionic gonadotropin, beta polypeptide 3
    • Follicle stimulating hormone alpha chain
    • follicle-stimulating hormone alpha chain
    • follicle-stimulating hormone alpha subunit
    • follitropin alpha chain
    • FSH Alpha
    • FSH-alpha
    • FSHA
    • glycoprotein hormones alpha chain
    • glycoprotein hormones, alpha polypeptide
    • GPHa
    • GPHA1
    • HCG
    • hCGB
    • Human Chorionic Gonadotropin
    • LHA
    • LSH alpha
    • LSH-alpha
    • luteinizing hormone alpha chain
    • lutropin alpha chain
    • Thyroid stimulating hormone alpha chain
    • thyroid-stimulating hormone alpha chain
    • thyrotropin alpha chain
    • TSH Alpha
    • TSH-alpha
    • TSHA
    see all
  • Relevance
    Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma.
  • Cellular localization


ab77874 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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All three of these proteins (ab51782, ab77874, and ab126652) are full length native human hCG with a molecular weight of 36.7 kDa, consisting of the alpha and beta chains (UniProt: P01215 and P01233). The proteins...

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Thank you for contacting Abcam regarding ab51782. I have received a reply from the laboratory about the use of this product in ELISA. The product has been used as a control in ELISA. If you can provide your protocol we would be happy to assist y...

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