The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
>95% by SDS-PAGE . ab188055 is prepared by proprietary fractionation methods.
Extinction Coefficient: 0.67.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -80°C.
Add deionized water or buffer to original or desired volume, aliquot and freeze unused portion. (50 ml before lyophilisation).
Albumin (32 AA)
Albumin (AA 34)
cell growth inhibiting protein 42
growth-inhibiting protein 20
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
Involvement in disease
Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
Belongs to the ALB/AFP/VDB family. Contains 3 albumin domains.
Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606. Glycated in diabetic patients. Phosphorylation sites are present in the extracelllular medium. Acetylated on Lys-223 by acetylsalicylic acid.