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Our portfolio of cell lines and lysates includes CRISPR knockouts, iPSC-derived neurons, along with standard cell lysates from a range of species and immortalized cell lines, and both healthy and diseased  tissue lysates. All our cell lines and lysates are validated in key applications and verified through abreviews by you.

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Features

Knock-out cell lines

​​Engineered and ready for you, find reliable, off-the-shelf, single-gene knock-outs in a number of immortalized cell backgrounds. 

 
 

Knock-out cell lysates 

Discover our range of knock-out cell lysates and get quick and simple solutions for your validation studies. 

 
 

Knock-out cell line publications

 

Read CRISPR knock-out cell line publications demonstrating the use of these CRISPR cell lines for a range of targets and applications.​

Knock-out cell line or lysate selection tool

Easily find out if you need a knock-out cell line or lysate to answer your research question. 

Custom CRISPR cell engineering services

Your edit, our expertise - engineered and ready for you. 

How can you use knock-out cell lines in your research?

Discover how you can save time with well-characterized and robust knock-out cell lines. 

  • All
  • Articles
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Maximize research efficiency on your return to the lab

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Improving efficiency in drug discovery

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Speed up progress and get results fast.

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Knock-out (KO) validation: confirming antibody specificity

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Antibody knock-out (KO) validation webinar | Abcam

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Understanding physiologically relevant pathways using Abcam's cell lines

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Knock-out (KO) cell lysates | Abcam

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How we validate our antibodies

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We know there is no one-size-fits-all CRISPR protocol so we will engineer the right gene-edit for your project.

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Protocols and troubleshooting tips, to help get the best from our antibodies

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Human iPSC-derived glutamatergic neurons for research and drug development

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5 steps to watch for when generating CRISPR KO cell lines

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KO cell line or lysate infographic

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Knock-out validation: Overcoming the perils of poor antibody specificity

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Custom cell lines: Factors to consider before you begin

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Applying CRISPR-edited cell lines to the drug discovery pipeline

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CRISPR to speed the drug pipeline

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CRISPR-Cas9: creating cell knock-outs

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CRISPR knock-out cell line publications

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