Knock-out cell lines
Product
CRISPR-Cas9 knock-out cell lines from Abcam provide you with reliable, off-the-shelf, single gene knockouts in common immortalized cell lines for target validation, pathway discovery, and more so you can confidently interrogate your target of interest.
Our cell lines portfolio includes commonly used human cancer cell lines, including HeLa and HEK293T, which can be used as a positive control for our knockout cell lines.
Obtaining your knock-out cell line is as easy as buying reagents.
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Five pillars to determine antibody specificity
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Antibody knock-out (KO) validation webinar | Abcam
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What is a clone number?
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Human NONO (nmt55 / p54nrb) knockout HEK-293T cell line (ab266244)
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Human VDAC3 knockout HEK-293T cell line (ab266066)
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Human NLRX1 knockout HeLa cell line (ab265964)
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Human CDC42EP4 knockout HeLa cell line (ab265954)
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Human CDC42EP4 knockout HeLa cell line (ab265954)
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Human POGK knockout HeLa cell line (ab265917)
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Human SRGN (Serglycin) knockout HeLa cell line (ab265911)
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Human CREB3L2 (BBF2H7) knockout HeLa cell line (ab265884)
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Human TFG (TRK fused gene) knockout HeLa cell line (ab265841)
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Human PPID (Cyclophilin 40) knockout HeLa cell line (ab265788)
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Human USP9X knockout HeLa cell line (ab265665)
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Human RANBP2 knockout HeLa cell line (ab265618)
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Human RANBP2 knockout HeLa cell line (ab265618)
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Human SLC20A2 (PIT2) knockout HeLa cell line (ab265574)
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Human MAPK7 (ERK5) knockout HeLa cell line (ab265508)
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Human DENR (Density Regulated Protein) knockout HeLa cell line (ab265473)
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Human ANKRD17 knockout HeLa cell line (ab265465)
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Human AXL knockout HeLa cell line (ab265392)
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Human CTDSPL knockout HeLa cell line (ab265366)
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Human FZD6 (Frizzled 6) knockout HeLa cell line (ab265280)
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Human DYRK3 knockout HeLa cell line (ab265198)
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Human PODXL knockout HeLa cell line (ab264984)
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Human PHF6 (PHD finger protein 6) knockout HeLa cell line (ab264902)
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Human SERPINB5 (MASPIN) knockout HeLa cell line (ab264750)
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Human ZMPSTE24 knockout HeLa cell line (ab264736)
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Human LAMP3 knockout HeLa cell line (ab264719)
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Human TNFRSF10A (DR4) knockout HeLa cell line (ab264687)
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Human P4HB knockout A-431 cell line (ab261887)
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Human AXL knockout HeLa cell line (ab261810)
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Human CXCL1 (GRO alpha) knockout HeLa cell line (ab261774)
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Human PHF6 (PHD finger protein 6) knockout HEK-293 cell line (ab261722)
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Human DDX17 knockout HEK-293 cell line (ab261721)
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Knock-out cell lines | Abcam
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Understanding physiologically relevant pathways using Abcam's cell lines
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Fast-track your research with CRISPR knock-out cell lines
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5 steps to watch for when generating CRISPR KO cell lines
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Cell engineering COVID-19 products
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KO cell line or lysate infographic
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Harnessing knockout validation for research reproducibility
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Knockout Cell Lines and Their Role in Confirming Antibody Specificity
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Knock-out validation: Overcoming the perils of poor antibody specificity
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Custom cell lines: Factors to consider before you begin
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Applying CRISPR-edited cell lines to the drug discovery pipeline
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CRISPR to speed the drug pipeline
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CRISPR-Cas9: creating cell knock-outs
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CRISPR knock-out cell line publications
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