Recombinant Anti-NBEAL2 antibody [EPR14501(B)] - N-terminal (ab187162)
![Western blot - Anti-NBEAL2 antibody [EPR14501(B)] - N-terminal (ab187162)](https://www.abcam.com/ps/products/187/ab187162/Images/ab187162-220356-anti-nbeal2-antibody-epr14501b-n-terminal-western-blot.jpg "Western blot - Anti-NBEAL2 antibody [EPR14501(B)] - N-terminal (ab187162)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR14501(B)] to NBEAL2 - N-terminal
- Suitable for: WB
- Reacts with: Human
Overview
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Product name
Anti-NBEAL2 antibody [EPR14501(B)] - N-terminal
See all NBEAL2 primary antibodies -
Description
Rabbit monoclonal [EPR14501(B)] to NBEAL2 - N-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide within Human NBEAL2 aa 1-100 (N terminal). The exact sequence is proprietary.
Database link: Q6ZNJ1 -
Positive control
- Human platelet lysate.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR14501(B) -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab187162 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000. Detects a band of approximately 303 kDa (predicted molecular weight: 303 kDa). |
Target
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Function
Probably involved in thrombopoiesis. Plays a role in the development or secretion of alpha-granules, that contain several growth factors important for platelet biogenesis. -
Tissue specificity
Expressed in megakaryocytes. -
Involvement in disease
Gray platelet syndrome -
Sequence similarities
Belongs to the WD repeat neurobeachin family.
Contains 1 BEACH domain.
Contains 5 WD repeats. -
Cellular localization
Endoplasmic reticulum. - Information by UniProt
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Database links
- Entrez Gene: 23218 Human
- Omim: 614169 Human
- SwissProt: Q6ZNJ1 Human
- Unigene: 437043 Human
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Alternative names
- BDPLT4 antibody
- GPS antibody
- NBEAL2 antibody
see all
Images
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Western blot - Anti-NBEAL2 antibody [EPR14501(B)] - N-terminal (ab187162)Anti-NBEAL2 antibody [EPR14501(B)] - N-terminal (ab187162) at 1/1000 dilution + Human platelet lysate at 10 µg
Secondary
Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution
Predicted band size: 303 kDa -
![Anti-NBEAL2 antibody [EPR14501(B)] - N-terminal (ab187162)](https://www.abcam.com/ps/products/187/ab187162/Images/ab187162-2-benefits-of-recombinant-antibodies.png)
Anti-NBEAL2 antibody [EPR14501(B)] - N-terminal (ab187162)
Datasheets and documents
Certificate of Compliance
References (1)
ab187162 has been referenced in 1 publication.
- Tomberg K et al. Spontaneous 8bp Deletion in Nbeal2 Recapitulates the Gray Platelet Syndrome in Mice. PLoS One 11:e0150852 (2016). WB . PubMed: 26950939
