Product nameNCKX2 peptide
Our Abpromise guarantee covers the use of ab5896 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity> 95 % SDS-PAGE.
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat Excanger (Na/Ca-k), catalog ab3507. Using a solution with equal weights per unit volume of peptide and corresponding antibody will yield a solution with a large molar excess of peptide that is able to competitively bind the antibody.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Na(+)/K(+)/Ca(2+) exchange protein 2
- Na(+)/K(+)/Ca(2+)-exchange protein 2
- NCKX 2
FunctionCritical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
Sequence similaritiesBelongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.
- Information by UniProt
ab5896 has not yet been referenced specifically in any publications.