Overview

  • Product name
    Anti-NCOA62 antibody [EPR9989(B)]
    See all NCOA62 primary antibodies
  • Description
    Rabbit monoclonal [EPR9989(B)] to NCOA62
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
    Unsuitable for: Flow Cyt,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human NCOA62 (UniProt Q13573).

  • Positive control
    • HeLa, A431, Raw264.7, NIH/3T3 and 293T cell lysates; A431 cells.
  • General notes

    Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab167165 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 61 kDa.
ICC/IF 1/100 - 1/250.
  • Application notes
    Is unsuitable for Flow Cyt,IHC-P or IP.
  • Target

    • Relevance
      Nuclear receptor coactivator NCoA62 (Nuclear Protein SkiP, SKIIP , ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.
    • Cellular localization
      Nuclear
    • Database links
    • Alternative names
      • Bx 42 antibody
      • Bx42 antibody
      • Homolog of Drosophila BX42 antibody
      • MGC119379 antibody
      • NCOA 62 antibody
      • Nuclear protein SkiP antibody
      • Nuclear receptor coactivator 62 kD antibody
      • Nuclear receptor coactivator NCoA 62 antibody
      • Nuclear receptor coactivator NCoA62 antibody
      • Prp 45 antibody
      • Prp45 antibody
      • PRPF 45 antibody
      • PRPF45 antibody
      • Ski interacting protein antibody
      • SKIIP antibody
      • SKIP antibody
      • SNW 1 antibody
      • SNW domain containing 1 antibody
      • SNW domain containing protein 1 antibody
      • SNW1 antibody
      • SNW1 protein antibody
      see all

    Images

    • All lanes : Anti-NCOA62 antibody [EPR9989(B)] (ab167165) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : A431 cell lysate
      Lane 3 : Raw264.7 cell lysate
      Lane 4 : NIH/3T3 cell lysate
      Lane 5 : 293T cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labeled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 61 kDa

    • Immunofluorescent analysis of A431 cells labeling NCOA62 with ab167165 at 1/100 dilution.

    References

    ab167165 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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