Overview

  • Product name

  • Description

    Rabbit polyclonal to NCR1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide corresponding to Human NCR1. (Near the C terminal; NP_001138929).
    Database link: O76036

  • Positive control

    • Mouse kidney tissue lysate; Human lymphoma tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.05% Sodium azide
    Constituents: 49% PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab199128 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/25 - 1/100.
WB 1/200 - 1/1000. Predicted molecular weight: 34 kDa.

Target

  • Function

    Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
  • Tissue specificity

    Selectively expressed by both resting and activated NK cells.
  • Sequence similarities

    Belongs to the natural cytotoxicity receptor (NCR) family.
    Contains 2 Ig-like (immunoglobulin-like) domains.
  • Post-translational
    modifications

    N-glycosylated.
    O-glycosylated.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Activating NK receptor NK p46 antibody
    • CD335 antibody
    • FLJ99094 antibody
    • hNKp46 antibody
    • Ly94 antibody
    • Lymphocyte antigen 94 antibody
    • Lymphocyte antigen 94 homolog (activating NK receptor; NK p46) antibody
    • Lymphocyte antigen 94 homolog antibody
    • Natural cytotoxicity triggering receptor 1 antibody
    • Natural killer cell p46-related protein antibody
    • NCR1 antibody
    • NCT1 antibody
    • NCTR1_HUMAN antibody
    • NK cell activating receptor antibody
    • NK cell-activating receptor antibody
    • NK-p46 antibody
    • NKp46 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human lymphoma tissue labeling NCR1 with ab199128 at 1/20 dilution.

  • Anti-NCR1 antibody (ab199128) at 1/450 dilution + Mouse kidney tissue lysate at 40 µg

    Predicted band size: 34 kDa



    Gel: 8% SDS-PAGE.

  • Immunofluorescence of Human lung cancer labeling NCR1 with ab199128 at 1:20. A FITC conjugated antibody was used as a secondry.

  • Immunofluorescence of Human esophagus cancer labeling NCR1 with ab199128 at 1:20. A FITC conjugated antibody was used as a secondry.

     

References

This product has been referenced in:

  • Matsuda M  et al. Human NK cell development in hIL-7 and hIL-15 knockin NOD/SCID/IL2rgKO mice. Life Sci Alliance 2:N/A (2019). Read more (PubMed: 30936185) »
  • Qiu Y  et al. Lactobacillus plantarum Enhanced IL-22 Production in Natural Killer (NK) Cells That Protect the Integrity of Intestinal Epithelial Cell Barrier Damaged by Enterotoxigenic Escherichia coli. Int J Mol Sci 18:N/A (2017). Read more (PubMed: 29137183) »
See all 4 Publications for this product

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