Overview

  • Product name

    NDSB-195, Zwitterionic non-detergent sulfobetaine
  • Description

    Zwitterionic non-detergent sulfobetaine.
  • Biological description

    Zwitterionic non-detergent sulfobetaine. Used to extract, solubilise and crystallise proteins. Prevents protein aggregation and promotes renaturation of denatured proteins.
  • Purity

    > 97%
  • CAS Number

    160255-06-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    3-[Ethyl(dimethyl)azaniumyl]propane-1-sulfonate
  • Molecular weight

    195.28
  • Molecular formula

    C7H17NO3S
  • PubChem identifier

    5221296
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC[N+](C)(C)CCCS(=O)(=O)[O-]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Suwa Y  et al. Preparation, crystallization and preliminary X-ray diffraction analysis of the DNA-binding domain of the Ets transcription factor in complex with target DNA. Acta Crystallogr Sect F Struct Biol Cryst Commun 64:171-4 (2008). Read more (PubMed: 18323600) »
  • Xiang L  et al. Interaction of anti-aggregation agent dimethylethylammonium propane sulfonate with acidic fibroblast growth factor. J Magn Reson 194:147-51 (2008). Read more (PubMed: 18617428) »
  • Pereira HM  et al. Cloning, expression and preliminary crystallographic studies of the potential drug target purine nucleoside phosphorylase from Schistosoma mansoni. Acta Crystallogr D Biol Crystallogr 59:1096-9 (2003). Read more (PubMed: 12777786) »

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