Key features and details
- Goat polyclonal to NDUFS7
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-NDUFS7 antibody
See all NDUFS7 primary antibodies
DescriptionGoat polyclonal to NDUFS7
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Goat, Cow, Dog, Chimpanzee, Gorilla
- WB: Human Heart lysate; IHC-P: Paraffin embedded Human Brain (Cortex) and Liver.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, Tris buffered saline
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab105025 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
Our Abpromise guarantee covers the use of ab105025 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 24 kDa).
1 hour primary incubation is recommended for this product.
|IHC-P||Use a concentration of 5 µg/ml.|
FunctionCore subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Involvement in diseaseLeigh syndrome
Mitochondrial complex I deficiency
Sequence similaritiesBelongs to the complex I 20 kDa subunit family.
- Information by UniProt
- CI 20 antibody
- CI-20kD antibody
- Complex I 20kDa subunit antibody
ab105025 has been referenced in 2 publications.
- Rao S et al. AIF-regulated oxidative phosphorylation supports lung cancer development. Cell Res 29:579-591 (2019). PubMed: 31133695
- Maio N et al. A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III. Cell Metab 25:945-953.e6 (2017). PubMed: 28380382