Overview

  • Product name

    Necrostatin-7, Necroptosis inhibitor
  • Description

    Necroptosis inhibitor
  • Biological description

    Necroptosis inhibitor. Structurally distinct from other necrostatins (Nec-1, Nec-3, Nec-4 and Nec-5).
  • Purity

    > 98%
  • CAS Number

    351062-08-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (Z)-5-((3-(4-Fluorophenyl)-1H-pyrazol-4-yl)methylene)-2-imino-3-(thiazol-2-yl)thiazolidin-4-one
  • Molecular weight

    371.41
  • Molecular formula

    C16H10FN5OS2
  • PubChem identifier

    1239801
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO and ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Fc1ccc(cc1)c4nncc4/C=C2\SC(=N)N(C2=O)c3nccs3
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Zheng W  et al. Structure-activity relationship study of a novel necroptosis inhibitor, necrostatin-7. Bioorg Med Chem Lett 18:4932-5 (2008). Read more (PubMed: 18768316) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab142132.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up