Product nameAnti-Nectin 2 antibody [R2.525]
See all Nectin 2 primary antibodies
DescriptionMouse monoclonal [R2.525] to Nectin 2
SpecificityRecognises CD112 Poliovirus Receptor Related 2 (PRR2), a new surface molecule, which has been reported to be homologous to the poliovirus receptor (CD155). Studies demonstrate that PRR2 expression is restrictred to the myelo-monocytic and megakaryocytic lineages. PRR2 expression has also been detected on haematopoeitic progenitors expressing CD34.
Tested applicationsSuitable for: Flow Cyt, IHC-Fr, IPmore details
Species reactivityReacts with: Human
The details of the immunogen for this antibody are not available.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.40
Preservative: 0.09% Sodium azide
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab23601 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-Fr: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionProbable cell adhesion protein.
Sequence similaritiesBelongs to the nectin family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Cellular localizationCell membrane.
- Information by UniProt
- CD 112 antibody
- CD112 antibody
- CD112 antigen antibody
ab23601 has been referenced in 1 publication.
- Cocchi F et al. Cell-to-cell spread of wild-type herpes simplex virus type 1, but not of syncytial strains, is mediated by the immunoglobulin-like receptors that mediate virion entry, nectin1 (PRR1/HveC/HIgR) and nectin2 (PRR2/HveB). J Virol 74:3909-17 (2000). PubMed: 10729168