Overview

  • Product name

    Nefiracetam, ACh and NMDA agonist
  • Description

    Nootropic agent. Potent ACh and NMDA agonist.
  • Biological description

    Nootropic. Potentiates ACh currents (EC50 = 1 nM, α4β2 receptor in cortical neurons) and NMDA currents, via interaction with the glycine binding site (EC50 = 10 nM). Shows potent neuroprotective effects and anticonvulsant effects in vivo.
  • Purity

    > 98%
  • CAS Number

    77191-36-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Kitano Y  et al. Effects of Nefiracetam, a novel pyrrolidone-type nootropic agent, on the amygdala-kindled seizures in rats. Epilepsia 46:1561-8 (2005). Read more (PubMed: 16190926) »
  • Ueda M  et al. The cognition-enhancer nefiracetam inhibits both necrosis and apoptosis in retinal ischemic models in vitro and in vivo. J Pharmacol Exp Ther 309:200-7 (2004). Read more (PubMed: 14718588) »
  • Narahashi T  et al. Mechanisms of action of cognitive enhancers on neuroreceptors. Biol Pharm Bull 27:1701-6 (2004). Read more (PubMed: 15516710) »

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