Anti-NEK8 antibody (ab169406)
Key features and details
- Mouse polyclonal to NEK8
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NEK8 antibody
See all NEK8 primary antibodies -
Description
Mouse polyclonal to NEK8 -
Host species
Mouse -
Tested Applications & Species
Application Species WB Human -
Immunogen
Full length Human NEK8 (amino acids 1-692; NP_835464.1).
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Positive control
- NEK8 transfected 293T cell lysate.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.4
Constituent: 99% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab169406 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
Application | Species |
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WB |
Human
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All applications |
Mouse
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Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 75 kDa.
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Notes |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 75 kDa. |
Target
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Function
Required for renal tubular integrity. -
Tissue specificity
Highest expression in thyroid, adrenal gland and skin. Low levels in spleen, colon and uterus. Overexpressed in breast tumors, with highest expression in infiltrating ductal carcinomas and moderate levels in mucinous adenocarcinoma. -
Sequence similarities
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
Contains 1 protein kinase domain.
Contains 5 RCC1 repeats. -
Cellular localization
Cytoplasm. Predominantly cytoplasmic. - Information by UniProt
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Database links
- Entrez Gene: 284086 Human
- Entrez Gene: 140859 Mouse
- Omim: 609799 Human
- SwissProt: Q86SG6 Human
- SwissProt: Q91ZR4 Mouse
- Unigene: 448468 Human
- Unigene: 23788 Mouse
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Alternative names
- JCK antibody
- NEK 8 antibody
- NEK12A antibody
see all
Images
Datasheets and documents
References (0)
ab169406 has not yet been referenced specifically in any publications.