Anti-NEK8 antibody (ab169406)
- Datasheet
- References
- Protocols
Overview
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Product nameAnti-NEK8 antibody
See all NEK8 primary antibodies -
DescriptionMouse polyclonal to NEK8
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Host speciesMouse
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Tested applicationsSuitable for: WBmore details
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Species reactivityReacts with: Human
Predicted to work with: Mouse
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Immunogen
Full length Human NEK8 (amino acids 1-692; NP_835464.1).
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Positive control
- NEK8 transfected 293T cell lysate.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
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Storage bufferpH: 7.20
Constituent: 99% PBS -
Concentration information loading... -
PurityProtein A purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab169406 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Predicted molecular weight: 75 kDa. |
Target
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FunctionRequired for renal tubular integrity.
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Tissue specificityHighest expression in thyroid, adrenal gland and skin. Low levels in spleen, colon and uterus. Overexpressed in breast tumors, with highest expression in infiltrating ductal carcinomas and moderate levels in mucinous adenocarcinoma.
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Sequence similaritiesBelongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
Contains 1 protein kinase domain.
Contains 5 RCC1 repeats. -
Cellular localizationCytoplasm. Predominantly cytoplasmic.
- Information by UniProt
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Database links
- Entrez Gene: 284086 Human
- Entrez Gene: 140859 Mouse
- Omim: 609799 Human
- SwissProt: Q86SG6 Human
- SwissProt: Q91ZR4 Mouse
- Unigene: 448468 Human
- Unigene: 23788 Mouse
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Alternative names
- JCK antibody
- NEK 8 antibody
- NEK12A antibody
see all
Images
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Western blot - Anti-NEK8 antibody (ab169406)All lanes : Anti-NEK8 antibody (ab169406) at 1 µg/ml
Lane 1 : NEK8 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Predicted band size: 75 kDa
Protocols
Datasheets and documents
References
ab169406 has not yet been referenced specifically in any publications.
