Nemadipine A, L-type calcium channel protein inhibitor (ab145991)

Overview

  • Product name

    Nemadipine A, L-type calcium channel protein inhibitor
  • Description

    Cell-permeable L-type calcium channel protein inhibitor
  • Biological description

    Cell-permeable L-type calcium channel protein inhibitor. Antagonizes α1-subunit of L-type calcium channel. Sensitizes cancer cells to TRAIL-induced apoptosis. 1,4-dihydropyridine (DHP) analog.
  • Purity

    > 97%
  • CAS Number

    54280-71-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Park SH  et al. Down-Regulation of Survivin by Nemadipine-A Sensitizes Cancer Cells to TRAIL-Induced Apoptosis. Biomol Ther (Seoul) 21:29-34 (2013). Read more (PubMed: 24009855) »
  • Stout RF & Parpura V Voltage-gated calcium channel types in cultured C. elegans CEPsh glial cells. Cell Calcium 50:98-108 (2011). Read more (PubMed: 21684004) »
  • Kwok TC  et al. A small-molecule screen in C. elegans yields a new calcium channel antagonist. Nature 441:91-5 (2006). Read more (PubMed: 16672971) »

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