Overview

  • Product name
    Anti-nephronectin antibody
    See all nephronectin primary antibodies
  • Description
    Rabbit polyclonal to nephronectin
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human nephronectin aa 264-292 conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q6UXI9

  • Positive control
    • MDA-MB453 cell line lysates

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99.9% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab173753 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab173753 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 62 kDa.

Target

  • Function
    Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha-8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins.
  • Tissue specificity
    Expressed in kidney and lung and to a lower extent in brain, pregnant uterus, placenta, thyroid gland and blood vessels.
  • Sequence similarities
    Belongs to the nephronectin family.
    Contains 5 EGF-like domains.
    Contains 1 MAM domain.
  • Developmental stage
    Expressed in fetal kidney, cochlea, eye, heart and lung.
  • Domain
    The MAM domain is required for localization at the cell surface.
  • Cellular localization
    Secreted > extracellular space > extracellular matrix. Trapped on the cell surface or in the extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • EGFL6L antibody
    • Nephronectin antibody
    • NPNT antibody
    • NPNT_HUMAN antibody
    • POEM antibody
    • Preosteoblast EGF like repeat protein with MAM domain antibody
    • Preosteoblast EGF-like repeat protein with MAM domain antibody
    • Protein EGFL6 like antibody
    • Protein EGFL6-like antibody
    see all

Images

  • MDA-MB453 cell lysate at 35 µg

    Predicted band size: 62 kDa

References

ab173753 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab173753.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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