Key features and details
- Goat polyclonal to NET1
- Suitable for: IHC-P
- Reacts with: Mouse, Rat, Dog, Human
- Isotype: IgG
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, Tris buffered saline
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab79006 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 2.5 µg/ml.|
FunctionActs as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
Tissue specificityWidely expressed.
Sequence similaritiesContains 1 DH (DBL-homology) domain.
Contains 1 PH domain.
Cellular localizationCytoplasm. Nucleus.
- Information by UniProt
- ARHG8_HUMAN antibody
- ARHGEF8 antibody
- GLYT2 antibody
ab79006 has been referenced in 1 publication.
- Liang X et al. VTIQ evaluates antitumor effects of NET-1 siRNA by UTMD in HCC xenograft models. Oncol Lett 16:2893-2902 (2018). PubMed: 30127877