Key features and details
- DNA minor groove binding ligand.
- CAS Number: 1438-30-8
- Purity: > 98%
- Soluble in water (1 mg/mL)
- Form / State: Solid
- Source: Streptomyces netropsis
Product nameNetropsin dihydrochloride, DNA minor groove binding ligand
DescriptionDNA minor groove binding ligand.
DNA minor groove binding ligand with potential antibiotic and antiviral properties. Binds to AT-rich regions in dsDNA, and has the ability to block DNA helicase, Topoisomerase and endonuclease, and also to interfere with transcription factor binding in these regions. Binds to dsDNA in a non-intercalative manner.
Chemical nameN-[4-[(3-Amino-3-iminopropyl)carbamoyl]-1-methylpyrrol-3-yl]-4-[[2-(diaminomethylideneamino)acetyl]amino]-1-methylpyrrole-2-carboxamide dihydrochloride
Storage instructionsStore at -20°C (desiccating conditions).
Solubility overviewSoluble in water (1 mg/mL)
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To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab146342 has not yet been referenced specifically in any publications.