Overview

  • Product name

    Anti-Neurobeachin antibody
    See all Neurobeachin primary antibodies
  • Description

    Rabbit polyclonal to Neurobeachin
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Human Neurobeachin (internal sequence). Gene Accssion: NP_056493
    Database link: Q8NFP9

  • Positive control

    • Human cervical cancer and Human ovarian cancer tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab198275 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/25 - 1/100.

Target

  • Function

    Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins.
  • Tissue specificity

    Predominant in many brain structures. Also expressed at medium levels in spleen, thymus, prostate, testis and ovary. Low level expression is seen in heart, kidney, pancreas, skeletal muscle and intestine.
  • Sequence similarities

    Belongs to the WD repeat neurobeachin family.
    Contains 1 BEACH domain.
    Contains 5 WD repeats.
  • Domain

    RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.
  • Cellular localization

    Cytoplasm. Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • BCL8B antibody
    • FLJ10197 antibody
    • KIAA1544 antibody
    • Lysosomal trafficking regulator 2 antibody
    • Lysosomal-trafficking regulator 2 antibody
    • LYST2 antibody
    • NBEA antibody
    • NBEA_HUMAN antibody
    • Neurobeachin antibody
    • Protein BCL8B antibody
    • Protein neurobeachin antibody
    • RP11-270C18.1 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue labeling Neurobeachin with ab198275 at 1/60.

  • Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue labeling Neurobeachin with ab198275 at 1/60.

References

ab198275 has not yet been referenced specifically in any publications.

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