Anti-Neurobeachin antibody (ab198275)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-Neurobeachin antibody
See all Neurobeachin primary antibodies -
Description
Rabbit polyclonal to Neurobeachin -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Synthetic peptide corresponding to Human Neurobeachin (internal sequence). Gene Accssion: NP_056493
Database link: Q8NFP9 -
Positive control
- Human cervical cancer and Human ovarian cancer tissues.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.3
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab198275 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | 1/25 - 1/100. |
Target
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Function
Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins. -
Tissue specificity
Predominant in many brain structures. Also expressed at medium levels in spleen, thymus, prostate, testis and ovary. Low level expression is seen in heart, kidney, pancreas, skeletal muscle and intestine. -
Sequence similarities
Belongs to the WD repeat neurobeachin family.
Contains 1 BEACH domain.
Contains 5 WD repeats. -
Domain
RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer. -
Cellular localization
Cytoplasm. Membrane. - Information by UniProt
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Database links
- Entrez Gene: 26960 Human
- Entrez Gene: 26422 Mouse
- Omim: 604889 Human
- SwissProt: Q8NFP9 Human
- SwissProt: Q9EPN1 Mouse
- Unigene: 491172 Human
- Unigene: 384353 Mouse
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Alternative names
- BCL8B antibody
- FLJ10197 antibody
- KIAA1544 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neurobeachin antibody (ab198275)Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue labeling Neurobeachin with ab198275 at 1/60.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neurobeachin antibody (ab198275)Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue labeling Neurobeachin with ab198275 at 1/60.
Protocols
Datasheets and documents
References
ab198275 has not yet been referenced specifically in any publications.
