Anti-Neurobeachin antibody (ab198275)
Key features and details
- Rabbit polyclonal to Neurobeachin
- Suitable for: IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-Neurobeachin antibody
See all Neurobeachin primary antibodies -
Description
Rabbit polyclonal to Neurobeachin -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Synthetic peptide corresponding to Human Neurobeachin (internal sequence). Gene Accssion: NP_056493
Database link: Q8NFP9 -
Positive control
- Human cervical cancer and Human ovarian cancer tissues.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab198275 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | 1/25 - 1/100. |
Target
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Function
Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. May anchor the kinase to cytoskeletal and/or organelle-associated proteins. -
Tissue specificity
Predominant in many brain structures. Also expressed at medium levels in spleen, thymus, prostate, testis and ovary. Low level expression is seen in heart, kidney, pancreas, skeletal muscle and intestine. -
Sequence similarities
Belongs to the WD repeat neurobeachin family.
Contains 1 BEACH domain.
Contains 5 WD repeats. -
Domain
RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer. -
Cellular localization
Cytoplasm. Membrane. - Information by UniProt
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Database links
- Entrez Gene: 26960 Human
- Entrez Gene: 26422 Mouse
- Omim: 604889 Human
- SwissProt: Q8NFP9 Human
- SwissProt: Q9EPN1 Mouse
- Unigene: 491172 Human
- Unigene: 384353 Mouse
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Alternative names
- BCL8B antibody
- FLJ10197 antibody
- KIAA1544 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neurobeachin antibody (ab198275)Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue labeling Neurobeachin with ab198275 at 1/60.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neurobeachin antibody (ab198275)Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue labeling Neurobeachin with ab198275 at 1/60.
Datasheets and documents
References (0)
ab198275 has not yet been referenced specifically in any publications.
