Product nameAnti-Neurogenin3/NGN-3 antibody
See all Neurogenin3/NGN-3 primary antibodies
DescriptionRabbit polyclonal to Neurogenin3/NGN-3
Tested applicationsSuitable for: WB, ICC/IFmore details
Species reactivityReacts with: Mouse, Rat, Human
Recombinant full length protein corresponding to Human Neurogenin3/NGN-3 aa 1-83.
MTPQPSGAPTVQVTRETERSFPRASEDEVTCPTSAPPSPTRTRGNCAEAE EGGCRGAPRKLRARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLN SALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADHSLYALE PPAPHCGELGSPGGSPGDWGSLYSPVSQAGSLSPAASLEERPGLLGATFS ACLSPGSLAFSDFL
Database link: Q9Y4Z2
- WB: HT-29, 293T and H460 cell lysates.
Previously labelled as Neurogenin3.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab176124 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 23 kDa.|
|ICC/IF||1/20 - 1/100.|
FunctionInvolved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types.
Involvement in diseaseDefects in NEUROG3 are the cause of diarrhea type 4 (DIAR4) [MIM:610370]. DIAR4 is a characterized by severe, life-threatening watery diarrhea associated with generalized malabsorption and a paucity of enteroendocrine cells.
Sequence similaritiesContains 1 basic helix-loop-helix (bHLH) domain.
- Information by UniProt
- ATH4B antibody
- Atoh5 antibody
- bHLHa7 antibody
All lanes : Anti-Neurogenin3/NGN-3 antibody (ab176124) at 1/1000 dilution
Lane 1 : HT-29 cell lysate
Lane 2 : 293T cell lysate
Lane 3 : H460 cell lysate
Lysates/proteins at 25 µg per lane.
All lanes : HRP Goat AntiRabbit IgG (H+L)
Developed using the ECL technique.
Predicted band size: 23 kDa
Exposure time: 90 seconds
Blocking buffer: 3% nonfat dry milk in TBST.
ab176124 has not yet been referenced specifically in any publications.