Key features and details
- Rabbit polyclonal to Neurogenin3/NGN-3
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-Neurogenin3/NGN-3 antibody
See all Neurogenin3/NGN-3 primary antibodies
DescriptionRabbit polyclonal to Neurogenin3/NGN-3
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat
- WB: Mouse liver tissue lysate IHC-P: Mouse small intestine tissue.
Previously labelled as Neurogenin3.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 1% BSA, 50% Glycerol
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab216885 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/500.|
|WB||1/300. Predicted molecular weight: 23 kDa.|
FunctionInvolved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types.
Involvement in diseaseDefects in NEUROG3 are the cause of diarrhea type 4 (DIAR4) [MIM:610370]. DIAR4 is a characterized by severe, life-threatening watery diarrhea associated with generalized malabsorption and a paucity of enteroendocrine cells.
Sequence similaritiesContains 1 basic helix-loop-helix (bHLH) domain.
- Information by UniProt
- ATH4B antibody
- Atoh5 antibody
- bHLHa7 antibody
Immunohistochemical analysis of formalin-fixed, paraffin-embedded mouse small intestine tissue, labeling Neurogenin3/NGN-3 with ab216885 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.
Anti-Neurogenin3/NGN-3 antibody (ab216885) at 1/300 dilution + Mouse liver tissue lysate
Predicted band size: 23 kDa
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human breast carcinoma tissue, labeling Neurogenin3/NGN-3 with ab216885 at 1/400 dilution, followed by conjugation to the secondary antibody and DAB staining.
ab216885 has been referenced in 1 publication.
- Gao Y et al. Role of TGF-ß/Smad Pathway in the Transcription of Pancreas-Specific Genes During Beta Cell Differentiation. Front Cell Dev Biol 7:351 (2019). PubMed: 31921861