Anti-Neurogenin3/NGN-3 antibody (ab216885)

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Overview

  • Product name

    Anti-Neurogenin3/NGN-3 antibody
    See all Neurogenin3/NGN-3 primary antibodies

  • Description

    Rabbit polyclonal to Neurogenin3/NGN-3

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IHC-P, WBmore details

  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat

  • Immunogen

    Synthetic peptide within Human Neurogenin3/NGN-3 aa 60-110 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    KLRARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGV L


    Database link: Q9Y4Z2

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • WB: Mouse liver tissue lysate IHC-P: Mouse small intestine tissue.

  • General notes

    Previously labelled as Neurogenin3.

Properties

Applications

Our Abpromise guarantee covers the use of ab216885 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.
WB 1/300. Predicted molecular weight: 23 kDa.

Target

  • Function

    Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types.

  • Involvement in disease

    Defects in NEUROG3 are the cause of diarrhea type 4 (DIAR4) [MIM:610370]. DIAR4 is a characterized by severe, life-threatening watery diarrhea associated with generalized malabsorption and a paucity of enteroendocrine cells.

  • Sequence similarities

    Contains 1 basic helix-loop-helix (bHLH) domain.

  • Cellular localization

    Nucleus.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • ATH4B antibody
    • Atoh5 antibody
    • bHLHa7 antibody
    • Class A basic helix-loop-helix protein 7 antibody
    • Math4B antibody
    • NEUROG3 antibody
    • Neurogenin-3 antibody
    • Neurogenin3 antibody
    • NGN-3 antibody
    • ngn3 antibody
    • NGN3_HUMAN antibody
    • OTTHUMP00000019730 antibody
    • Protein atonal homolog 5 antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neurogenin3/NGN-3 antibody (ab216885)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neurogenin3/NGN-3 antibody (ab216885)

    Immunohistochemical analysis of formalin-fixed, paraffin-embedded mouse small intestine tissue, labeling Neurogenin3/NGN-3 with ab216885 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

  • Western blot - Anti-Neurogenin3/NGN-3 antibody (ab216885)
    Western blot - Anti-Neurogenin3/NGN-3 antibody (ab216885)
    Anti-Neurogenin3/NGN-3 antibody (ab216885) at 1/300 dilution + Mouse liver tissue lysate

    Predicted band size: 23 kDa

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neurogenin3/NGN-3 antibody (ab216885)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neurogenin3/NGN-3 antibody (ab216885)

    Immunohistochemical analysis of formalin-fixed, paraffin-embedded human breast carcinoma tissue, labeling Neurogenin3/NGN-3 with ab216885 at 1/400 dilution, followed by conjugation to the secondary antibody and DAB staining.

References

ab216885 has not yet been referenced specifically in any publications.

Publishing research using ab216885? Please let us know so that we can cite the reference in this datasheet.

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