Overview

  • Product name

    Anti-Neuroglycan C antibody
    See all Neuroglycan C primary antibodies
  • Description

    Rabbit polyclonal to Neuroglycan C
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Neuroglycan C aa 380-430 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: O95196

  • Positive control

    • Human U251 cell lysates; mouse cerebrum lysates; rat brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab218137 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Predicted molecular weight: 60 kDa.
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation.
  • Tissue specificity

    Restricted to brain (at protein level).
  • Sequence similarities

    Contains 1 EGF-like domain.
  • Developmental stage

    Expressed in brain of 3 months, 5 and 10-year-old individuals.
  • Post-translational
    modifications

    N-glycosylated.
    O-glycosylated; contains chondroitin sulfate glycans. Part-time proteoglycan, expressed in part as a proteoglycan exhibiting chondroitin sulfate glycans and in part as a non-proteoglycan form. The relative amount of both forms depends on tissues and tissues maturation.
    Phosphorylated; in intracellular and extracellular parts.
  • Cellular localization

    Cell membrane. Endoplasmic reticulum membrane. Golgi apparatus membrane. In neurons, localizes to synaptic junctions (By similarity). Also detected in the endoplasmic reticulum and the Golgi (By similarity). Partially enriched in lipid rafts.
  • Information by UniProt
  • Database links

  • Alternative names

    • Acidic leucine rich EGF like domain containing brain protein antibody
    • Acidic leucine-rich EGF-like domain-containing brain protein antibody
    • Caleb antibody
    • Chondroitin sulfate proteoglycan 5 (neuroglycan C) antibody
    • Chondroitin sulfate proteoglycan 5 antibody
    • CSPG5 antibody
    • CSPG5_HUMAN antibody
    • MGC44034 antibody
    • Neuroglycan C antibody
    • Ngc antibody
    • OTTHUMP00000164796 antibody
    • OTTHUMP00000164797 antibody
    • OTTHUMP00000210429 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded rat brain tissue labeling Neuroglycan C with ab218137 at 1/300 dilution, followed by conjugation to the secondary antibody and DAB staining.

  • Anti-Neuroglycan C antibody (ab218137) at 1/300 dilution + Human U251 cell lysate

    Secondary
    onjugated secondary antibody at 1/10000 dilution

    Predicted band size: 60 kDa

  • Anti-Neuroglycan C antibody (ab218137) at 1/300 dilution + mouse cerebrum lysate

    Secondary
    conjugated secondary antibody at 1/10000 dilution

    Predicted band size: 60 kDa

References

ab218137 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab218137.
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