Overview

  • Product name

    Anti-Neurokinin A antibody
    See all Neurokinin A primary antibodies
  • Description

    Rabbit polyclonal to Neurokinin A
  • Host species

    Rabbit
  • Specificity

    This antibody is specific for Neurokinin A.
  • Tested applications

    Suitable for: RIA, ELISAmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Chicken, Guinea pig, Hamster, Cow, Alligator
  • Immunogen

    Synthetic peptide:

    YHKTDSFVGLM

    (Human) conjugated to KLH via carboxyl group.

Properties

Applications

Our Abpromise guarantee covers the use of ab48598 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
RIA Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.

Target

  • Relevance

    Neurokinin A is a member of the tachykinin family of peptides. Like substance P, neuropeptide K and neuropeptide gamma, it is generated by cleavage of the protachykinin 1 precursor. Neurokinin A localises to neurons in the central and peripheral nervous systems, and is particularly abundant in the gastrointestinal tract. The biological actions of neurokinin A are similar to those of substance P, and include vasodilation and stimulation of smooth muscle contraction.
  • Cellular localization

    Secreted
  • Database links

  • Alternative names

    • Neurokinin alpha antibody
    • NeurokininA antibody
    • NK A antibody
    • NKN A antibody
    • NPK antibody
    • PPT antibody
    • TAC1 antibody
    see all

References

This product has been referenced in:

  • Delvalle NM  et al. Communication Between Enteric Neurons, Glia, and Nociceptors Underlies the Effects of Tachykinins on Neuroinflammation. Cell Mol Gastroenterol Hepatol 6:321-344 (2018). Read more (PubMed: 30116771) »
  • Murthy RG  et al. Tac1 regulation by RNA-binding protein and miRNA in bone marrow stroma: Implication for hematopoietic activity. Brain Behav Immun 22:442-50 (2008). Read more (PubMed: 18061399) »
See all 2 Publications for this product

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Application
Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample
Human Tissue sections (Nasal mucosa)
Permeabilization
No
Specification
Nasal mucosa

Mr. Duc Dung Le

Verified customer

Submitted Apr 29 2015

Application
Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample
Mouse Tissue sections (Brain)
Permeabilization
No
Specification
Brain
Blocking step
Serum as blocking agent for 45 minute(s) · Concentration: 5% · Temperature: RT°C
Fixative
Zamboni

Mr. Duc Dung Le

Verified customer

Submitted Apr 29 2015

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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