Anti-Neurokinin A antibody [C1] (ab239503)

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Overview

  • Product name

    Anti-Neurokinin A antibody [C1]
    See all Neurokinin A primary antibodies

  • Description

    Mouse monoclonal [C1] to Neurokinin A

  • Host species

    Mouse

  • Tested applications

    Suitable for: IHC-P, WBmore details

  • Species reactivity

    Reacts with: Rat, Human, Pig

  • Immunogen

    Synthetic peptide corresponding to Human Neurokinin A aa 98-107 conjugated to ovalbumin.
    Database link: P20366

  • Positive control

    • WB: Pig liver and cerebrum lysates; rat cerebrum lysate; HEK-293T cell lysate. IHC-P: Human prostate tissue.

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...

  • Purity

    Protein A purified

  • Purification notes

    Antigen-specific affinity chromatography followed by Protein A affinity chromatography. Purified from TCS.

  • Clonality

    Monoclonal

  • Clone number

    C1

  • Isotype

    IgG2b

  • Light chain type

    kappa

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab239503 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 - 20 µg/ml.
WB Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 15 kDa.

Target

  • Relevance

    Neurokinin A is a member of the tachykinin family of peptides. Like substance P, neuropeptide K and neuropeptide gamma, it is generated by cleavage of the protachykinin 1 precursor. Neurokinin A localises to neurons in the central and peripheral nervous systems, and is particularly abundant in the gastrointestinal tract. The biological actions of neurokinin A are similar to those of substance P, and include vasodilation and stimulation of smooth muscle contraction.

  • Cellular localization

    Secreted

  • Database links

    • Alternative names

      • Neurokinin alpha antibody
      • NeurokininA antibody
      • NK A antibody
      • NKN A antibody
      • NPK antibody
      • PPT antibody
      • TAC1 antibody
      see all

    Images

    • Western blot - Anti-Neurokinin A antibody [C1] (ab239503)
      Western blot - Anti-Neurokinin A antibody [C1] (ab239503)
      Anti-Neurokinin A antibody [C1] (ab239503) at 5 µg/ml + Pig liver lysate

      Predicted band size: 15 kDa

    • Western blot - Anti-Neurokinin A antibody [C1] (ab239503)
      Western blot - Anti-Neurokinin A antibody [C1] (ab239503)
      Anti-Neurokinin A antibody [C1] (ab239503) at 5 µg/ml + Rat cerebrum lysate

      Predicted band size: 15 kDa

    • Western blot - Anti-Neurokinin A antibody [C1] (ab239503)
      Western blot - Anti-Neurokinin A antibody [C1] (ab239503)
      Anti-Neurokinin A antibody [C1] (ab239503) at 5 µg/ml + Pig cerebrum lysate

      Predicted band size: 15 kDa

    • Western blot - Anti-Neurokinin A antibody [C1] (ab239503)
      Western blot - Anti-Neurokinin A antibody [C1] (ab239503)
      Anti-Neurokinin A antibody [C1] (ab239503) at 5 µg/ml + HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate

      Predicted band size: 15 kDa

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neurokinin A antibody [C1] (ab239503)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Neurokinin A antibody [C1] (ab239503)

      Paraffin-embedded human prostate tissue stained for Neurokinin A using ab239503 at 20 μg/ml in immunohistochemical analysis. DAB staining.

    References

    ab239503 has not yet been referenced specifically in any publications.

    Publishing research using ab239503? Please let us know so that we can cite the reference in this datasheet.

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