Anti-Neuroligin 1 antibody (ab153821)
Key features and details
- Rabbit polyclonal to Neuroligin 1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Neuroligin 1 antibody
See all Neuroligin 1 primary antibodies -
Description
Rabbit polyclonal to Neuroligin 1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Cow -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 119-295 of Human Neuroligin 1.
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Positive control
- U87-MG whole cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab153821 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 94 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 94 kDa. |
Target
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Function
Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. Seems to play role in formation or maintenance of synaptic junctions. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. -
Tissue specificity
Expressed in the blood vessel walls (at protein level). -
Sequence similarities
Belongs to the type-B carboxylesterase/lipase family. -
Cellular localization
Cell membrane. Cell junction > synapse. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. - Information by UniProt
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Database links
- Entrez Gene: 22871 Human
- Entrez Gene: 192167 Mouse
- Omim: 600568 Human
- SwissProt: Q8N2Q7 Human
- SwissProt: Q99K10 Mouse
- Unigene: 478289 Human
- Unigene: 316080 Mouse
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Alternative names
- NLG 1 antibody
- KIAA1070 antibody
- MGC45115 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab153821 has been referenced in 3 publications.
- Xu J et al. Regulation of the Proliferation of Diabetic Vascular Endothelial Cells by Degrading Endothelial Cell Functional Genes with QKI-7. Contrast Media Mol Imaging 2022:6177809 (2022). PubMed: 35711530
- Xu K et al. CircGRIA1 shows an age-related increase in male macaque brain and regulates synaptic plasticity and synaptogenesis. Nat Commun 11:3594 (2020). PubMed: 32681011
- Yang C et al. Targeting QKI-7 in vivo restores endothelial cell function in diabetes. Nat Commun 11:3812 (2020). PubMed: 32732889