Anti-Neuroligin 1 antibody (ab36131)

This fast track antibody is not yet fully characterized. It is subject to these terms and conditions.

Overview

Properties

Applications

  • Application notes
    This antibody gave a positive result in ELISA against the immunizing peptide. Antibody detection limit dilution 1:4,000.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. Seems to play role in formation or maintenance of synaptic junctions. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses.
    • Tissue specificity
      Expressed in the blood vessel walls (at protein level).
    • Sequence similarities
      Belongs to the type-B carboxylesterase/lipase family.
    • Cellular localization
      Cell membrane. Cell junction > synapse. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities.
    • Information by UniProt
    • Database links
    • Alternative names
      • NLG 1 antibody
      • KIAA1070 antibody
      • MGC45115 antibody
      • Neuroligin-1 antibody
      • NL1 antibody
      • NLG1 antibody
      • Nlgn1 antibody
      • NLGN1_HUMAN antibody
      see all

    References

    ab36131 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Application
    Immunocytochemistry
    Sample
    Rat Cultured Cells (neurons)
    Specification
    neurons
    Fixative
    Methanol
    Permeabilization
    No
    Blocking step
    BSA as blocking agent for 15 minute(s) · Concentration: 0.3% · Temperature: 20°C

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    Verified customer

    Submitted Feb 07 2011

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