Overview

  • Product name

    Anti-Neuroligin 2 antibody
    See all Neuroligin 2 primary antibodies
  • Description

    Rabbit polyclonal to Neuroligin 2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human Neuroligin 2 (internal sequence). NP_065846.1
    Database link: Q8NFZ4

  • Positive control

    • HeLa lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab177107 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 91 kDa (predicted molecular weight: 91 kDa).

Target

  • Relevance

    Neuroligins are cell adhesion proteins that are thought to instruct the formation and alignment of synaptic specializations. The three known rodent neuroligin isoforms share homologous extracellular acetylcholinesterase-like domains that bridge the synaptic cleft and bind beta-neurexins. All neuroligins have identical intracellular C-terminal motifs that bind to PDZ domains of various target proteins. Neuroligin 2 is exclusively localized to inhibitory synapses in rat brain and dissociated neurons. In immature neurons, neuroligin 2 is found at synapses and also at GABAA receptor aggregates that are not facing presynaptic termini.
  • Cellular localization

    Cell Membrane
  • Database links

  • Alternative names

    • KIAA1366 antibody
    • MGC67386 antibody
    • NL2 antibody
    • NLGN2 antibody
    • Ortholog of human and rat neuroligin 2 NLGN2 antibody
    • OTTHUMP00000135277 antibody
    • OTTMUSP00000006214 antibody
    • RP23-422L16.24 antibody
    see all

Images

  • Anti-Neuroligin 2 antibody (ab177107) at 1/500 dilution + HeLa lysate

    Predicted band size: 91 kDa

References

This product has been referenced in:

  • Kanellopoulos AH  et al. Mapping protein interactions of sodium channel NaV1.7 using epitope-tagged gene-targeted mice. EMBO J 37:427-445 (2018). Read more (PubMed: 29335280) »
See 1 Publication for this product

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