Key features and details
- Rabbit polyclonal to Neuroligin 2
- Suitable for: ELISA
- Isotype: IgG
Product nameAnti-Neuroligin 2 antibody
See all Neuroligin 2 primary antibodies
Predicted to work with: Mouse, Rat, Human
Synthetic peptide corresponding to Human Neuroligin 2 aa 650-750 conjugated to keyhole limpet haemocyanin.
(Peptide available as
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
Concentration information loading...
PurityImmunogen affinity purified
|ELISA||Use at an assay dependent concentration. This antibody gave a positive result in ELISA against the immunizing peptide (ab36601).|
RelevanceNeuroligins are cell adhesion proteins that are thought to instruct the formation and alignment of synaptic specializations. The three known rodent neuroligin isoforms share homologous extracellular acetylcholinesterase-like domains that bridge the synaptic cleft and bind beta-neurexins. All neuroligins have identical intracellular C-terminal motifs that bind to PDZ domains of various target proteins. Neuroligin 2 is exclusively localized to inhibitory synapses in rat brain and dissociated neurons. In immature neurons, neuroligin 2 is found at synapses and also at GABAA receptor aggregates that are not facing presynaptic termini.
Cellular localizationCell Membrane
- KIAA1366 antibody
- MGC67386 antibody
- NL2 antibody
ab36602 has been referenced in 2 publications.
- Heshmati M et al. Cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility. Proc Natl Acad Sci U S A 115:1111-1116 (2018). PubMed: 29339486
- Swaminathan A et al. Non-canonical mTOR-Independent Role of DEPDC5 in Regulating GABAergic Network Development. Curr Biol 28:1924-1937.e5 (2018). PubMed: 29861134