Anti-Neuroligin 3 antibody (ab172798)
- Datasheet
- References
- Protocols
Overview
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Product nameAnti-Neuroligin 3 antibody
See all Neuroligin 3 primary antibodies -
DescriptionMouse polyclonal to Neuroligin 3
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Host speciesMouse
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Tested applicationsSuitable for: WBmore details
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Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
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Immunogen
Full length protein corresponding to Human Neuroligin 3 aa 1-828.
Sequence:MWLRLGPPSLSLSPKPTVGRSLCLTLWFLSLALRASTQAPAPTVNTHFGK LRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPYWSGIRNAT HFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPT EDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMID GSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSE NIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS WAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARY HVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDP EDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETR RKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSD AAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDP NKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATK VAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWSTK RPAISPAYSNENAQGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASILF LNVLAFAALYYRKDKRRQEPLRQPSPQRGAWAPELGAAPEEELAALQLGP THHECEASPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSLVG LQTLHPYNTFAAGFNSTGLPHSHSTTRV
Database link: AAH51715.1 -
Positive control
- Neuroligin 3 transfected 293T cell lysate
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
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Storage bufferpH: 7.2
Constituent: 100% PBS -
Concentration information loading... -
PurityProtein A purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Related Products
Applications
Our Abpromise guarantee covers the use of ab172798 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Predicted molecular weight: 92 kDa. |
Target
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FunctionCell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system.
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Tissue specificityExpressed in the blood vessel walls (at protein level). Detected in throughout the brain and in spinal cord. Detected in brain, and at lower levels in pancreas islet beta cells.
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Involvement in diseaseAutism, X-linked 1 (AUTSX1) [MIM:300425]: A complex multifactorial, pervasive developmental disorder characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age. Most individuals with autism also manifest moderate mental retardation. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
X-linked Asperger syndrome 1 (ASPGX1) [MIM:300494]: Considered to be a form of childhood autism. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry. -
Sequence similaritiesBelongs to the type-B carboxylesterase/lipase family.
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Cellular localizationCell membrane. Cell junction > synapse. Detected at both glutamatergic and GABAergic synapses.
- Information by UniProt
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Database links
- Entrez Gene: 54413 Human
- Entrez Gene: 245537 Mouse
- Entrez Gene: 171297 Rat
- Omim: 300336 Human
- SwissProt: Q9NZ94 Human
- SwissProt: Q8BYM5 Mouse
- SwissProt: Q62889 Rat
- Unigene: 438877 Human
see all -
Alternative names
- Gliotactin homolog antibody
- HNL3 antibody
- Neuroligin-3 antibody
see all
Images
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Western blot - Anti-Neuroligin 3 antibody (ab172798)All lanes : Anti-Neuroligin 3 antibody (ab172798) at 1 µg/ml
Lane 1 : Neuroligin 3 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Predicted band size: 92 kDa
Datasheets and documents
Protocols
References
ab172798 has not yet been referenced specifically in any publications.
