Product nameNeuromedin B (porcine), Bombesin-like peptide
DescriptionBombesin-like peptide; endogenous ligand for the neuromedin B receptor
Biological descriptionMammalian bombesin-like peptide and endogenous ligand for the neuromedin B receptor (IC50 = 2 nM). Elicits a diverse range of biological functions including endocrine and exocrine secretions, smooth muscle contractility, neuronal excitability and cellular growth.
SequenceGNLWATGHFM (Modifications: C-terminal amide)
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
This product has been referenced in:
- Ohki-Hamazaki H Neuromedin B. Prog Neurobiol 62:297-312 (2000). Read more (PubMed: 10840151) »
- Sainz E et al. Four amino acid residues are critical for high affinity binding of neuromedin B to the neuromedin B receptor. J Biol Chem 273:15927-32 (1998). Read more (PubMed: 9632639) »
- Minamino N et al. Neuromedin B: a novel bombesin-like peptide identified in porcine spinal cord. Biochem Biophys Res Commun 114:541-8 (1983). Read more (PubMed: 6882442) »