Anti-Neuropeptide Y antibody (ab10341)
Key features and details
- Guinea pig polyclonal to Neuropeptide Y
- Suitable for: IHC-FoFr
- Reacts with: Rat
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-Neuropeptide Y antibody
See all Neuropeptide Y primary antibodies -
Description
Guinea pig polyclonal to Neuropeptide Y -
Host species
Guinea pig -
Tested applications
Suitable for: IHC-FoFrmore details -
Species reactivity
Reacts with: Rat
Predicted to work with: Sheep, Chicken, Cow, Human, Pig, Macaque monkey
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Immunogen
Synthetic peptide corresponding to Rat Neuropeptide Y aa 50-150.
Database link: P07808 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituent: Whole serum -
Concentration information loading... -
Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab10341 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-FoFr |
1/500. Please note the recommended fixative if paraformaldehyde + picric acid, see recommended protocol for details.
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| Notes |
|---|
|
IHC-FoFr
1/500. Please note the recommended fixative if paraformaldehyde + picric acid, see recommended protocol for details. |
Target
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Function
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. -
Tissue specificity
One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla. -
Sequence similarities
Belongs to the NPY family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 396464 Chicken
- Entrez Gene: 504216 Cow
- Entrez Gene: 4852 Human
- Entrez Gene: 397304 Pig
- Entrez Gene: 24604 Rat
- Omim: 162640 Human
- SwissProt: P28673 Chicken
- SwissProt: Q6RUW3 Cow
see all -
Alternative names
- C-flanking peptide of NPY antibody
- CPON antibody
- Neuropeptide tyrosine antibody
see all
Images
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Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Neuropeptide Y antibody (ab10341)ab10341, at a dilution of 1/500, staining Neuropeptide Y in rat hypothalamus by Immunohistochemistry (PFA perfusion fixed frozen sections).
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Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Neuropeptide Y antibody (ab10341)ab10341, at a dilution of 1/500, staining of striatal rat interneurones (arrows) by Immunohistochemistry (PFA perfusion fixed frozen sections).
Datasheets and documents
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Datasheet download
References (7)
ab10341 has been referenced in 7 publications.
- Suzuki M et al. Anti-nerve growth factor therapy attenuates cutaneous hypersensitivity and musculoskeletal discomfort in mice with osteoporosis. Pain Rep 3:e652 (2018). PubMed: 29922744
- Yang JJ et al. KATP Channels Mediate Differential Metabolic Responses to Glucose Shortage of the Dorsomedial and Ventrolateral Oscillators in the Central Clock. Sci Rep 7:640 (2017). PubMed: 28377630
- Ouellet L & de Villers-Sidani E Trajectory of the main GABAergic interneuron populations from early development to old age in the rat primary auditory cortex. Front Neuroanat 8:40 (2014). IHC-FoFr ; Rat . PubMed: 24917792
- Priddle TH & Crow TJ Protocadherin 11X/Y a Human-Specific Gene Pair: an Immunohistochemical Survey of Fetal and Adult Brains. Cereb Cortex : (2012). IHC-P ; Human . PubMed: 22744706
- Wu Q et al. Loss of GABAergic signaling by AgRP neurons to the parabrachial nucleus leads to starvation. Cell 137:1225-34 (2009). IHC-FoFr ; Mouse . PubMed: 19563755
- Bletsa A et al. Sensory pulpal nerve fibres and trigeminal ganglion neurons express IL-1RI: a potential mechanism for development of inflammatory hyperalgesia. Int Endod J 42:978-86 (2009). PubMed: 19732182
- Krauss M et al. Spermidine synthase is prominently expressed in the striatal patch compartment and in putative interneurones of the matrix compartment. J Neurochem 97:174-89 (2006). PubMed: 16515550
