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Anti-Neuropeptide Y antibody (ab10341)

  • Datasheet
  • SDS
Reviews (2) Submit a question References (7)

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Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Neuropeptide Y antibody (ab10341)
  • Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Neuropeptide Y antibody (ab10341)

Key features and details

  • Guinea pig polyclonal to Neuropeptide Y
  • Suitable for: IHC-FoFr
  • Reacts with: Rat
  • Isotype: IgG

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Overview

  • Product name

    Anti-Neuropeptide Y antibody
    See all Neuropeptide Y primary antibodies
  • Description

    Guinea pig polyclonal to Neuropeptide Y
  • Host species

    Guinea pig
  • Tested Applications & Species

    Application Species
    IHC-FoFr
    Rat
    See all applications and species data
  • Immunogen

    Synthetic peptide:

    SDLLMRESTENAPRTR

    , corresponding to amino acids 76-91 of Rat Neuropeptide Y
    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.05% Sodium azide
    Constituent: Whole serum
  • Concentration information loading...
  • Purity

    Whole antiserum
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Neuroscience
    • Neurotransmitter
    • Neuropeptides
    • Hormones
    • Neuroscience
    • Neurotransmitter
    • Neuropeptides
    • More Neuropeptides
    • Cardiovascular
    • Angiogenesis
    • Angiogenic Factors
    • Neuroscience
    • Neurology process
    • Metabolism
    • Cardiovascular
    • Heart
    • Hypertrophy
    • Other
    • Cardiovascular
    • Heart
    • Contractility
    • Inotropics
    • Cardiovascular
    • Vasculature
    • Vasoconstriction
    • Other
    • Metabolism
    • Types of disease
    • Cancer

Associated products

  • Recombinant Protein

    • Recombinant Human Neuropeptide Y protein (ab112330)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab10341 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application Species
IHC-FoFr
Rat
All applications
Sheep
Chicken
Cow
Human
Pig
Macaque monkey
Application Abreviews Notes
IHC-FoFr
1/500. Please note the recommended fixative if paraformaldehyde + picric acid, see recommended protocol for details.
Notes
IHC-FoFr
1/500. Please note the recommended fixative if paraformaldehyde + picric acid, see recommended protocol for details.

Target

  • Function

    NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
  • Tissue specificity

    One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla.
  • Sequence similarities

    Belongs to the NPY family.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession P01303 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 396464 Chicken
    • Entrez Gene: 504216 Cow
    • Entrez Gene: 4852 Human
    • Entrez Gene: 397304 Pig
    • Entrez Gene: 24604 Rat
    • Omim: 162640 Human
    • SwissProt: P28673 Chicken
    • SwissProt: Q6RUW3 Cow
    • SwissProt: P01303 Human
    • SwissProt: P01304 Pig
    • SwissProt: P07808 Rat
    • Unigene: 1832 Human
    • Unigene: 9714 Rat
    see all
  • Alternative names

    • C-flanking peptide of NPY antibody
    • CPON antibody
    • Neuropeptide tyrosine antibody
    • Neuropeptide Y precursor antibody
    • NPY antibody
    • NPY_HUMAN antibody
    • Pro neuropeptide Y antibody
    • PYY 4 antibody
    • PYY4 antibody
    • Y Neuropeptide antibody
    see all

Images

  • Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Neuropeptide Y antibody (ab10341)
    Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Neuropeptide Y antibody (ab10341)
    ab10341, at a dilution of 1/500, staining Neuropeptide Y in rat hypothalamus by Immunohistochemistry (PFA perfusion fixed frozen sections).
  • Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Neuropeptide Y antibody (ab10341)
    Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Neuropeptide Y antibody (ab10341)
    ab10341, at a dilution of 1/500, staining of striatal rat interneurones (arrows) by Immunohistochemistry (PFA perfusion fixed frozen sections).

Protocols

  • Recommended IHC-FrFr protocol with ab10341

Click here to view the general protocols

Datasheets and documents

  • SDS download

  • Datasheet download

    Download

References (7)

Publishing research using ab10341? Please let us know so that we can cite the reference in this datasheet.

ab10341 has been referenced in 7 publications.

  • Suzuki M  et al. Anti-nerve growth factor therapy attenuates cutaneous hypersensitivity and musculoskeletal discomfort in mice with osteoporosis. Pain Rep 3:e652 (2018). PubMed: 29922744
  • Yang JJ  et al. KATP Channels Mediate Differential Metabolic Responses to Glucose Shortage of the Dorsomedial and Ventrolateral Oscillators in the Central Clock. Sci Rep 7:640 (2017). PubMed: 28377630
  • Ouellet L & de Villers-Sidani E Trajectory of the main GABAergic interneuron populations from early development to old age in the rat primary auditory cortex. Front Neuroanat 8:40 (2014). IHC-FoFr ; Rat . PubMed: 24917792
  • Priddle TH & Crow TJ Protocadherin 11X/Y a Human-Specific Gene Pair: an Immunohistochemical Survey of Fetal and Adult Brains. Cereb Cortex : (2012). IHC-P ; Human . PubMed: 22744706
  • Wu Q  et al. Loss of GABAergic signaling by AgRP neurons to the parabrachial nucleus leads to starvation. Cell 137:1225-34 (2009). IHC-FoFr ; Mouse . PubMed: 19563755
  • Bletsa A  et al. Sensory pulpal nerve fibres and trigeminal ganglion neurons express IL-1RI: a potential mechanism for development of inflammatory hyperalgesia. Int Endod J 42:978-86 (2009). PubMed: 19732182
  • Krauss M  et al. Spermidine synthase is prominently expressed in the striatal patch compartment and in putative interneurones of the matrix compartment. J Neurochem 97:174-89 (2006). PubMed: 16515550

Customer reviews and Q&As

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1-2 of 2 Abreviews or Q&A

Immunohistochemistry (Frozen sections) abreview for Anti-Neuropeptide Y antibody

Inconclusive
Abreviews
Abreviews
abreview image
Application
Immunohistochemistry (Frozen sections)
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: r.t°C
Sample
Rat Tissue sections (Brain)
Specification
Brain
Permeabilization
Yes - 0.2% Triton X-100
Fixative
Paraformaldehyde
Read More

Dr. Fabio Canneva

Verified customer

Submitted Jul 10 2014

Immunohistochemistry (Frozen sections) abreview for Anti-Neuropeptide Y antibody

Poor
Abreviews
Abreviews
Application
Immunohistochemistry (Frozen sections)
Sample
Mouse Tissue sections (Brain- coronal sections including the hypothalamus)
Specification
Brain- coronal sections including the hypothalamus
Fixative
Paraformaldehyde
Permeabilization
No
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 50% · Temperature: 20°C
Read More

Abcam user community

Verified customer

Submitted Jul 14 2008

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