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Astrocytes are star-shaped glial cellst that serve a wide variety of functions in the central nervous system. They are vital for brain development, physiology and pathology.
Glial fibrillary acidic protein (GFAP) is an intermediate filament and major component of the astrocyte cytoskeleton.
We recommend Recombinant Anti-GFAP antibody [EPR1034Y] (ab68428).
Image (left): Human hippocampus tissue section stained with anti-GFAP (ab68428).
Excitatory amino acid transporter 1 (EAAT1) is an astrocyte-specific glutamate transporter. It may also be known as glutamate aspartate Transporter (GLAST).
Image (left): Rat cerebral cortex tissue sections stained with anti-EAAT1 (ab181036).
Excitatory amino acid transporter 2 (EAAT2) is an astrocyte-specific glutamate transporter. EAAT2 has many alternative names including solute carrier family 1 member 2 (SLC1A2) and glutamate transporter 1 (GLT-1).
We recommend Recombinant Anti-EAAT2 antibody [EPR19798] (ab205248).
|Selective EAAT2 inhibitor||Dihydrokainic acid (ab120066)|
|Stimulator of EAAT2 expression||Ceftriaxone (ab120871)|
|Potent and competitive EAAT1-4 inhibitor||L-(-)-threo-3-Hydroxyaspartic acid (ab146130)|
|Potent and competitive EAAT2, EAAT4 and EAAT5 inhibitor||L-trans-Pyrrolidine-2,4-dicarboxylic acid (ab146131)|
Image (left): Mouse striatum tissue sections stained with anti-EAAT2 (green) (ab205248).
This enzyme is involved in the metabolism of nitrogen. In the brain it is primarily found in astrocytes.
Image (left): Mouse cerebrum tissue sections stained with anti-glutamine synthetase (green) (ab176562).
This is a calcium binding protein, also found in oligodendrocyte precursor cells (OPCs). Double labeling with NG2 will distinguish the OPCs from the astrocytes.
Image (left): Rat cerebrum tissue sections stained with anti-S100 beta (green) (ab52642).
Aldehyde dehydrogenase 1 family member L1 is an enzyme that catalyzes the conversion of 10-formyltetrahydrofolate, NADP+ and water to tetrahydrofolate, NADPH and CO2.
Image (left): Human kidney tissue sections stained with anti-ALDH1L1 (ab177463).