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In the brains of Parkinson's disease patients, native alpha-synuclein misfolds and aggregates to form filamentous Lewy bodies. Anti-alpha synuclein filament antibody (ab209530) is a conformation-specific antibody that detects aggregated alpha-synuclein.
Immunohistochemistry (formaldehyde-fixed paraffin-embedded sections) of human DLB brain stained with anti-alpha synuclein filament antibody [MJFR14-6-4-2] (ab209538). Click here for further information on the experimental conditions used for this experiment. Image courtesy of Mr Carl Hobbs, Kings College London.