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Commonly used markers for GABAergic neurons
GABAergic neurons generate gamma aminobutyric acid (GABA), one of the two inhibitory neurotransmitters in the central nervous system (CNS).
GABA transporter 1 (GAT1)
A transporter on the cell membrane that moves GABA into the cell.
Mouse brain tissue sections stained with anti-GABA transporter 1 (ab64645).
|NNC 711 (ab120364)||Potent, selective GAT1 inhibitor|
|Tiagabine hydrochloride (ab120237)||Selective GAT1 inhibitor|
GABAB receptor 1 and 2
GABAB receptors are metabotropic transmembrane receptors for GABA that are linked via G-proteins to potassium channels. GABAB receptor 1 and GABAB receptor 2 assemble as heterodimers in neuronal membranes.
Rat brain (hippocampus) stained with anti-GABA B receptor 1 (red) (ab55051).
GABAB receptor modulators
|Saclofen (ab120327)||Selective GABAB receptor agonist|
|(R)-Baclofen (ab120325)||GABAB receptor agonist|
|CGP 35348 (ab120167)||GABAB receptor agonist|
|CGP 7930 (ab120492)||Positive GABAB receptor allosteric modulator|
|GS 39783 (ab120320)||Novel GABAB positive allosteric modulator|