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We've put together the most common markers for GABAergic neurons to help you identify your neuronal population.
GABA transporter 1 (GAT1) | GABAB receptors 1 and 2 | Glutamate decarboxylase isoforms (GAD65 and GAD67)
GABAergic neurons produce gamma-Aminobutyric acid (GABA), the main inhibitory neurotransmitter in the mammalian central nervous system (CNS).
Dysfunction of GABA neurotransmission can result in several disorders, including schizophrenia and epilepsy.
Mouse brain tissue sections stained with anti-GABA transporter 1 (ab64645).
Browse all GABA transporter 1 antibodies
Product | Activity |
NNC 711 (ab120364) | Potent, selective GAT1 inhibitor Potent, selective GAT-1 inhibitor |
Tiagabine hydrochloride (ab120237) | Selective GAT1 inhibitor |
Rat brain (hippocampus) stained with anti-GABAB receptor 1 (red) (ab55051).
Product | Activity |
Saclofen (ab120327) | Selective GABAB receptor agonist |
(R)-Baclofen (ab120325) | GABAB receptor agonist |
CGP 35348 (ab120167) | GABAB receptor agonist |
CGP 7930 (ab120492) | Positive GABAB receptor allosteric modulator |
GS 39783 (ab120320) | Novel GABAB positive allosteric modulator |
The 65 kDa isomorph of glutamate decarboxylase that catalyzes the formation of GABA from glutamate.
Rat cerebellar cortex labeled with anti-GAD65 (ab26113).
The 67 kDa isomorph of glutamate decarboxylase. Unlike GAD65, which is also expressed in the pancreas, GAD67 is CNS-specific.
Mouse cerebellum sections stained with anti-GAD67 (ab26116).
References