For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome

We use cookies to make our site as useful as possible.

Our Cookie Policy explains how you can opt-out of the cookies we use.

If you continue without changing your cookie settings, we'll assume you’re happy with this.

Continue Continue

United States
Your country/region is currently set to:

If incorrect, please enter your country/region into the box below, to view site information related to your country/region.

Call (888) 77-ABCAM (22226) or contact us
Need help? Contact us

  • My account
  • Sign out
Sign in or Register with us

Welcome

Sign in or

Don't have an account?

Register with us
My basket
Quick order
Abcam homepage

  • Research Products
    By product type
    Primary antibodies
    Secondary antibodies
    ELISA and Matched Antibody Pair Kits
    Cell and tissue imaging tools
    Cellular and biochemical assays
    Proteins and Peptides
    By product type
    Proteomics tools
    Agonists, activators, antagonists and inhibitors
    Cell lines and Lysates
    Multiplex miRNA assays
    Multiplex Assays
    By research area
    Cancer
    Cardiovascular
    Cell Biology
    Epigenetics
    Metabolism
    Developmental Biology
    By research area
    Immunology
    Microbiology
    Neuroscience
    Signal Transduction
    Stem Cells
  • Diagnostic & Therapeutic Solutions
    Custom solutions & partnerships

    Custom antibody development and commercial partnerships to advance your diagnostic and therapeutic discovery.

    Create custom solutions with us

    Partner with us

  • Support
    Support hub

    Access advice and support for any research roadblock

    View support hub

    Protocols

    Your experiments laid out step by step

    View protocols

  • Events
    • Conference calendar
    • Cancer
    • Cardiovascular
    • Epigenetics & Nuclear signaling
    • Immunology
    • Neuroscience
    • Stem cells
    • Tradeshows
    • Scientific webinars
    Keep up to date with the latest events

    Full event breakdown with abstracts, speakers, registration and more

    View global event calendar

  • Pathways
    Cell signalling pathways

    View all pathways

    View all interactive pathways

Supporting our customers and employees during the COVID-19 pandemic. Read more

MAP2 antibody (ab5392)

Mature neuron markers

Related

  • Back to neural markers guide
    • Directly conjugated neural markers
      • Your guide to optimizing IHC experiments
        • Brdu staining protocol
          • Caged neurotransmitters for precision release
            • Video protocols library
              • Get your personalised updates from Abcam
                • Mature neuron marker panel

                  A quick reference guide to mature neuron markers

                  Mature neurons are terminally differentiated and are no longer able to divide. Their purpose is to receive, process, and transfer information in the central and peripheral nervous systems. 

                  NeuN
                  An RNA binding protein that is highly specific for post-mitotic neurons. However, the following cell types do not express NeuN:

                  • ​Golgi cells​
                  • Purkinje cells
                  • Olfactory bulb mitral cells
                  • Retinal photoreceptor cells
                  • Inferior olivary and dentate nucleus neurons
                  • Sympathetic ganglion cells

                  Mouse cerebrum sections stained with anti-NeuN (green) (ab177487).

                  Browse all NeuN antibodies​​

                  Read about the advantages of our NeuN recombinant rabbit monoclonal antibody (ab177487)


                  ​MAP2

                  A neuron-specific protein that promotes assembly and stability of the microtubule network.

                  Mouse cortex tissue stained with anti-MAP2 (green) (ab183830).

                  ​​​Browse all MAP2 antibodies​


                  160 kDa Neurofilament medium
                  Major intermediate filament found in neurons.

                  Human brain tissue stained using ​anti-160 kDa neurofilament medium (ab68142).

                  Browse all 160 kDa neurofilament medium antibodies


                  ​​Neurofilament heavy

                  Major intermediate filament found in neurons.

                  Mouse hippocampus tissue stained using anti-neurofilament heavy (green) (ab207176).

                  Browse all neurofilament heavy antibodies


                  Synaptophysin
                  Synaptic vesicle protein that regulates vesicle endocytosis in neurons.

                  Human iPS cell-derived neurons stained with anti-synaptophysin (green) (ab32127).

                  Browse all synaptophysin antibodies


                  PSD95
                  Synaptic protein that associates with receptors and the cytoskeleton.

                  Mouse retina tissue stained with anti-PSD95 (green) (ab238135).

                  Browse all PSD95 antibodies

                  ​



                  ​

                  References

                  • El-Husseini, A. E. et al. PSD-95 involvement in maturation of excitatory synapses. Science 290, 1364–8 (2000).
                    Kwon, S. E. & Chapman, E. R. Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons. Neuron 70, 847–54 (2011).
                    Mullen, R. J., Buck, C. R. & Smith, A. M. NeuN, a neuronal specific nuclear protein in vertebrates. Development 116, 201–211 (1992).
                    Soltani, M. H. et al. Microtubule-associated protein 2, a marker of neuronal differentiation, induces mitotic defects, inhibits growth of melanoma cells, and predicts metastatic potential of cutaneous melanoma. Am. J. Pathol. 166, 1841–1850 (2005).
                    Trojanowski, J. Q., Walkenstein, N. & Lee, V. M. Expression of neurofilament subunits in neurons of the central and peripheral nervous system: an immunohistochemical study with monoclonal antibodies. J. Neurosci. 6, 650–660 (1986).
                    Yuan, a., Rao, M. V., Veeranna & Nixon, R. a. Neurofilaments at a glance. J. Cell Sci. 125, 3257–3263 (2012).
                    El-Husseini, A. E. et al. PSD-95 involvement in maturation of excitatory synapses. Science 290, 1364–8 (2000).
                  • Kwon, S. E. & Chapman, E. R. Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons. Neuron 70, 847–54 (2011).
                  • Mullen, R. J., Buck, C. R. & Smith, A. M. NeuN, a neuronal specific nuclear protein in vertebrates. Development 116, 201–211 (1992).
                  • Soltani, M. H. et al. Microtubule-associated protein 2, a marker of neuronal differentiation, induces mitotic defects, inhibits growth of melanoma cells, and predicts metastatic potential of cutaneous melanoma. Am. J. Pathol. 166, 1841–1850 (2005).
                  • Trojanowski, J. Q., Walkenstein, N. & Lee, V. M. Expression of neurofilament subunits in neurons of the central and peripheral nervous system: an immunohistochemical study with monoclonal antibodies. J. Neurosci. 6, 650–660 (1986).
                  • Yuan, a., Rao, M. V., Veeranna & Nixon, R. a. Neurofilaments at a glance. J. Cell Sci. 125, 3257–3263 (2012).


                  Get resources and offers direct to your inbox Sign up
                  A-Z by research area
                  • Cancer
                  • Cardiovascular
                  • Cell biology
                  • Developmental biology
                  • Epigenetics & Nuclear signaling
                  • Immunology
                  • Metabolism
                  • Microbiology
                  • Neuroscience
                  • Signal transduction
                  • Stem cells
                  A-Z by product type
                  • Primary antibodies
                  • Secondary antibodies
                  • Biochemicals
                  • Isotype controls
                  • Flow cytometry multi-color selector
                  • Kits
                  • Loading controls
                  • Lysates
                  • Peptides
                  • Proteins
                  • Slides
                  • Tags and cell markers
                  • Tools & Reagents
                  Help & support
                  • Support
                  • Make an Inquiry
                  • Protocols & troubleshooting
                  • Placing an order
                  • RabMAb products
                  • Biochemical product FAQs
                  • Training
                  • Browse by Target
                  Company
                  • Corporate site
                  • Investor relations
                  • Company news
                  • Careers
                  • About us
                  • Blog
                  Events
                  • Tradeshows
                  • Conferences
                  International websites
                  • abcam.cn
                  • abcam.co.jp

                  Join with us

                  • LinkedIn
                  • facebook
                  • Twitter
                  • YouTube
                  • Terms of sale
                  • Website terms of use
                  • Cookie policy
                  • Privacy policy
                  • Legal
                  • Modern slavery statement
                  © 1998-2021 Abcam plc. All rights reserved.