Neural markers

​​Neurons and glia express unique sets of transcription factors, enzymes, cytoskeletal proteins, and receptors. Ensure you are choosing the best neural subtype markers with our easy-to-use guides. 

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Synaptic transmission

Synaptic transmission is the process by which signaling neurotransmitters are released by the pre-synaptic neuron and subsequently bind and activate receptors of the postsynaptic neuron.

During synaptic transmission, neurotransmitters accumulate in synaptic vesicles and are released by exocytosis from the pre-synaptic neuron. The neurotransmitters subsequently diffuse across the synaptic cleft, bind and activate receptors of the postsynaptic neuron.

Binding then provokes an electrical change in the post-synaptic neuron. Following release from the pre-synaptic neuron, neurotransmitters are rapidly removed, either by enzymatic destruction or by re-uptake into the pre-synaptic neuron.

Neurotransmitters during synaptic transmission

There are a large number of neurotransmitter types. Common neurotransmitter types are:

There are a variety of key receptors and transporters which play an important role in synaptic transmission and are essential in transporting the various neurotransmitters across biological membranes to various cellular and subcellular locations.

Summary of neural markers