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Alzheimer's disease is classically characterized by misfolded aggregates of Aß and tau proteins, forming plaques and tangles in the brain. However, emerging evidence indicates that neuroinflammation, mediated by activated glial cells, plays a fundamental role in Alzheimer's disease pathogenesis. Consequently, understanding the interplay between the immune and nervous systems might be the key to prevention or delay of neurodegenerative diseases.
This poster provides an overview of roles of Aß and tau in Alzheimer's disease and shows the involvement of microglia and asrocytes in producing an inflammatory environment.