Overview

  • Product name

    Anti-Neurotensin Receptor 1/NTSR1 antibody
    See all Neurotensin Receptor 1/NTSR1 primary antibodies
  • Description

    Rabbit polyclonal to Neurotensin Receptor 1/NTSR1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Human Neurotensin Receptor 1/NTSR1 (internal sequence) conjugated to keyhole limpet haemocyanin. (CAA49675.1)

  • Positive control

    • Human pancreas tissue; MCF7 cell extract.
  • General notes

     This product was previously labelled as Neurotensin Receptor 1

     

Properties

Applications

Our Abpromise guarantee covers the use of ab117592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 46 kDa.
ELISA 1/1000.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Relevance

    Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. NTR1 has been reported in brain, pancreas, and small intestine. ESTs have been isolated from brain and colon libraries.
  • Cellular localization

    Cell Membrane, Endoplasmic reticulum, Golgi Apparatus and Plasma membrane. Integral membrane protein.
  • Database links

  • Alternative names

    • High affinity levocabastine insensitive neurotensin receptor antibody
    • Neurotensin receptor 1 (high affinity) antibody
    • Neurotensin receptor type 1 antibody
    • NT R 1 antibody
    • NTR antibody
    • NTR1 antibody
    • NTR1_HUMAN antibody
    • NTRH antibody
    • NTRR antibody
    • NTSR 1 antibody
    see all

Images

  • ab117592, at 5 µg/ml, staining Neurotensin Receptor 1/NTSR1 in Formalin-fixed, Paraffin-embedded Human Pancreas tissue by Immunohistochemistry.

  • All lanes : Anti-Neurotensin Receptor 1/NTSR1 antibody (ab117592) at 1/500 dilution

    Lane 1 : MCF7 cell extract
    Lane 2 : MCF7 cell extract with immunizing peptide

    Predicted band size: 46 kDa

References

This product has been referenced in:

  • Su ZJ  et al. Neurotensin promotes cholangiocarcinoma metastasis via the EGFR/AKT pathway. Gene 687:143-150 (2019). Read more (PubMed: 30359740) »
  • Yin X  et al. Evaluation of neurotensin receptor 1 as a potential imaging target in pancreatic ductal adenocarcinoma. Amino Acids 49:1325-1335 (2017). Read more (PubMed: 28536844) »
See all 5 Publications for this product

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