Overview

  • Product name

    Anti-Neurotensin Receptor 1/NTSR1 antibody
    See all Neurotensin Receptor 1/NTSR1 primary antibodies
  • Description

    Guinea pig polyclonal to Neurotensin Receptor 1/NTSR1
  • Host species

    Guinea pig
  • Tested applications

    Suitable for: WB, IHC-Fr, ICC/IFmore details
  • Species reactivity

    Reacts with: Rat
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Rat Neurotensin Receptor 1/NTSR1 aa 279-302.
    Sequence:

    TVGTHNGLEHSTFNMTIEPGRVQAYC

  • General notes

     This product was previously labelled as Neurotensin Receptor 1

     

Properties

Applications

Our Abpromise guarantee covers the use of ab66216 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000. Detects a band of approximately 47 kDa (predicted molecular weight: 47 kDa).
IHC-Fr 1/1000.
ICC/IF 1/1000.

Target

  • Relevance

    Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. NTR1 has been reported in brain, pancreas, and small intestine. ESTs have been isolated from brain and colon libraries.
  • Cellular localization

    Cell Membrane, Endoplasmic reticulum, Golgi Apparatus and Plasma membrane. Integral membrane protein.
  • Database links

  • Alternative names

    • High affinity levocabastine insensitive neurotensin receptor antibody
    • Neurotensin receptor 1 (high affinity) antibody
    • Neurotensin receptor type 1 antibody
    • NT R 1 antibody
    • NTR antibody
    • NTR1 antibody
    • NTR1_HUMAN antibody
    • NTRH antibody
    • NTRR antibody
    • NTSR 1 antibody
    see all

Images

  • Top image: Light microscopic analysis of NTSR1 expression in primary afferent neurons (arrows) using 1:1000 ab66216 of PFA fixed cells.
    Bottom image: At higher magnification, neurons exhibit a cytoplasmic pattern of immunoreactivity (arrowheads).
  • All lanes : Anti-Neurotensin Receptor 1/NTSR1 antibody (ab66216) at 1/5000 dilution

    Lane 1 : DRG's
    Lane 2 : Lumbar spinal chord
    Lane 3 : brain

    Lysates/proteins at 25 µg per lane.

    Predicted band size: 47 kDa
    Observed band size: 47 kDa

References

ab66216 has not yet been referenced specifically in any publications.

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