Product nameAnti-Neurturin antibody
See all Neurturin primary antibodies
DescriptionRabbit polyclonal to Neurturin
Tested applicationsSuitable for: WB, ICC/IFmore details
Species reactivityReacts with: Human
Full length protein corresponding to Human Neurturin aa 96-197. Recombinant Human Neurturin protein produced using CHO-suspension cell line, and then purified from the cell culture supernatant
ARLGARPCGLRELEVRVSELGLGYASDETVLFRYCAGACEAAARVYDLGL RRLRQRRRLR RERVRAQPCCRPTAYEDEVSFLDAHSRYHTVHELSARE CACV
Database link: Q99748
- Human Neurturin expressed in CHOEBNALT85 cell culture supernatant.
As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Constituents: 99% PBS, Ammonium sulphate
Concentrated ammonium sulphate
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab205558 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 22 kDa.|
|ICC/IF||Use a concentration of 0.5 - 2 µg/ml.|
FunctionSupports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
Involvement in diseaseDefects in NRTN are a cause of Hirschsprung disease (HSCR) [MIM:142623]. In association with mutations of RET gene, and possibly with other loci, defects in NRTN are involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.
Sequence similaritiesBelongs to the TGF-beta family. GDNF subfamily.
- Information by UniProt
- Neurturin antibody
- Neurturin precursor antibody
- NRTN antibody
All lanes : Anti-Neurturin antibody (ab205558) at 1/5000 dilution
Lane 1 : Human Neurturin expressed in CHOEBNALT85 cell culture supernatant
Lane 2 : non transfected CHOEBNALT85 cell culture supernatant
Lysates/proteins at 5 µl per lane.
All lanes : Rabbit Anti-Chicken IgY H&L (HRP) (ab6753)
Predicted band size: 22 kDa
ab205558 has not yet been referenced specifically in any publications.